| About this Abstract |
| Meeting |
2020 TMS Annual Meeting & Exhibition
|
| Symposium
|
Recent Advances in Functional Materials and 2D/3D Processing for Sensors and Electronic Applications
|
| Presentation Title |
D-23: A Novel Electrochemical Sensor for Determination of DNA Damage Biomarkers in Biological Fluids using Two-dimensional (2D) Layered Nanomaterial (Mxene) Covered Binary Metal Sulfide Nanocomposite |
| Author(s) |
Sea-Fue Wang, Govindasamy Mani |
| On-Site Speaker (Planned) |
Sea-Fue Wang |
| Abstract Scope |
To explore a novel and two-dimensional (2D) layered nanomaterial (mxene) covered binary metal sulfide (mxene@CuMoS2) as an electrode material by hydrothermal technique. Herein, novel nanocomposite is successfully characterized by various characterization analysis (FESEM, HRTEM, XRD, XPS and EIS). The nanomaterial is employed as a high sensitive electrochemical sensor for the determination of cancer and oxidative biomarker (8-hydroxy-2’-deoxyguanosine and 4-nitrotyrosine). The results demonstrated that the mxene@CuMoS2 modified screen-printed carbon electrode. The high sensitive properties of the optimized flower like CuMoS2 modified nanocatalyst are because of the excellent synergistic effect of the CuMoS2 flower and 2D mxene nanosheets, as evidenced by a superior (bio) sensing performance. The nanocomposite fabricated modified non-enzymatic biosensor was facilitating the analysis with wide linear ranges and nanomolar detection limit. The mxene@CuMoS2 modified sensor can also employed and promising its application towards the quantification of cancer biomarker in biological samples (urine and serum). |
| Proceedings Inclusion? |
Planned: Supplemental Proceedings volume |