The goal of this presentation is to offer a personal viewpoint on the differing roles and responsibilities, from a leadership vantage point, of scientists and faculty at a National Laboratory and University, respectively. Specifically, the expectations for success at both organizations will be compared and contrasted based upon performance criteria and reward systems. While both types of organizations recognize excellence, particularly on innovative and impactful research, the differing customer and value systems do not translate seamlessly between the organizations. Recommendations for navigating both environments, both pro and con opinions, will be presented. Examples of successfully implemented programs that increase success rates of early career faculty will be shared. Moreover, ideas on how transitioning connections and networking can be leveraged for opportunities will be discussed.