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Meeting Materials Science & Technology 2020
Symposium Synthesis, Characterization, Modeling and Applications of Functional Porous Materials
Presentation Title Development of Nanostructured Vycor Glass Microspheres for Doxorubicin Administration
Author(s) Bryan Escalante Castro, Yanina Martinez, Guillermo Zampieri, Yrina Viatela
On-Site Speaker (Planned) Bryan Escalante Castro
Abstract Scope In the present work, nanostructured porous SiO2 microspheres were developed for future drug release applications of doxorubicin. The glass has a nominal composition of 65.6SiO2 27.8 B 2 O 3 6.0Na 2 O0.6Al 2 O 3 weight percent. Microspheres with a regular morphology and 25-35m size were made by flame spheroidization method. The porous microspheres were obtained by a thermal separation treatment at 660C for 6 and 10 hours so two immiscible phases were obtained one is rich in silica and the other one is rich in boron and sodium. After the lixiviation for 2 and 4 days, SEM images showed a greater interconnectivity of the pores as the phase separation time increased. The composition is mostly SiO2 studied by EDS and XPS Spectrofluorimetry of intensity vs concentration of doxorubicin showed a LogNormal distribution in deionized water. These results are important to relate release studies and pi-stacking of the drug.

OTHER PAPERS PLANNED FOR THIS SYMPOSIUM

An Overview of High-temperature Ceramic-carbonate Dual-phase Membranes for CO2 Capture and Conversion
Compositional Influence on Kirkendall Pore Formation during Fabrication of Gamma Prime Strengthened Superalloy Microtubes
Crystallinity Effect on Mesoporous TiO2 Nanoparticle Negative Electrode Material for Metal Ion Batteries
Density Functional Theory Study of the Porous Metal-organic Framework Material Ni-Bpy-Me
Designing Multi-phase Reaction Pathways for CO2 Capture and Enhanced H2 Production from Ca- and Mg-bearing Precursors to Produce Stable Porous Carbonates Using Cross-scale X-ray Scattering Measurements
Development of Nanostructured Vycor Glass Microspheres for Doxorubicin Administration
Experimental Thermodynamics of Zeolites and Metal-organic Frameworks
Hierarchical Porosity in δ-MnO2 Nanosheet Assemblies via Layer-tunnel Conversion
Highly Controlled and Steerable Porosity for Ceramic Structures via Freeze Casting
Introductory Comments: Synthesis, Characterization, Modeling and Applications of Functional Porous Materials
Low/Intermediate Temperature Polysiloxane Derived Ceramics with Increased Carbon for Electrical Applications
Luminescent Metal-organic Framework-Based Sensors of Rare Earth Elements in Aqueous Streams
Porous Crystalline Porphyrinic Structures for Functional Materials Applications
Porous Organic Cage Composite Membranes for Post-combustion CO2 Separation
Surface Modified ScSZ-MC Dual-phase Membrane for Pre-combustion CO2 Capture
Synchrotron Structure and Sorption Properties of a Metal Organic Framework Compound Ni(3-methyl-4,4’-bipyridine)[Ni(CN)4] for CO2 Mitigation Application
The Influence of Yttria Content and Synthetic Parameters on the Thermal Stability of Yttria-stabilized Zirconia Aerogels
Thermodynamics of Naturally Occurring 2D and 3D Mineral Hosts: Zeolites, Layered Double Hydroxides and Clays

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