| About this Abstract |
| Meeting |
2020 TMS Annual Meeting & Exhibition
|
| Symposium
|
Nanocomposites VI: Nanoscience and Nanotechnology in Advanced Composites
|
| Presentation Title |
Comparative Cytotoxicity and Photothermal Study of Graphene Oxide (Go), Graphene Quantum Dots (Gqds) And Gqds/Go-Gold Nanorod Conjugates Against Different Cancer Cell Lines |
| Author(s) |
Samuel Oluwatobi Oluwafemi, Thabang C Lebepe, Tetsuya Kodama |
| On-Site Speaker (Planned) |
Samuel Oluwatobi Oluwafemi |
| Abstract Scope |
We herein report the synthesis of graphene oxide, graphene quantum dots and their conjugation to two different near infrared gold nanorods (AuNRs). All the as-synthesised materials were stable in biological media, PBS and over different pH range (4-14). The cell viability and photothermal efficiency of all the as-synthesised material were tested against four different cancer cell lines. The graphene materials were shown to be less toxic than the AuNRs alone.The GO increased the cell viability by increasing the cell attachement and proliferation of cells. However, when the GO composites are irradiated with the laser, the cells were destroyed. These results shows that the GO /GQDs – AuNRs nanocomposite possed good biocompatibility and excellent photothermal efficiency. Hence, the as-synthesised nanocomposites will be efficient materials for therapeutic application. |
| Proceedings Inclusion? |
Planned: |