|About this Abstract
||Materials Science & Technology 2020
||Surface Treatments and Properties of Titanium and Titanium Alloys: A Forum on New Strategies and Processes for Biomedical and Industrial Advanced Applications
||Sustainable Antibacterial Activity of Iodine-loaded Bioactive Titanium Metal by Chemical and Heat Treatment
||Seiji Yamaguchi, Morihiro Ito, Seine A. Shintani, Takashi Nakamura, Hiroaki Takadama
|On-Site Speaker (Planned)
The demand for prevention of infection as well as faster bone bonding is sharply increasing in orthopaedic and dental implants. In this study, conventional NaOH solution and heat treatment that allows Ti and its alloys bond to living bone was modified to induce calcium and iodine ions into the metal surfaces. As a result, iodine-containing calcium titanate with the 7.3 – 10.3 % of iodine was produced on the metals. The treated metals formed bone-like apatite in a simulated body fluid within 3 days, and exhibited high antibacterial activity against to methicillin-resistant Staphylococcus aureus, Staphylococcus aureus, and Escherichia coli (more than 99% reduction) without any cytotoxicity. This high reduction rate of bacteria almost maintained even if the treated Ti had been preserved under simulated body environment for a long period of half year (97.3% reduction). The treated metals with iodine-containing calcium titanate should be useful for orthopaedic and dental implants.
||Planned: The journal 'Materials' is planning a special issue with papers from this symposium