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Meeting Materials Science & Technology 2020
Symposium Surface Treatments and Properties of Titanium and Titanium Alloys: A Forum on New Strategies and Processes for Biomedical and Industrial Advanced Applications
Presentation Title Sustainable Antibacterial Activity of Iodine-loaded Bioactive Titanium Metal by Chemical and Heat Treatment
Author(s) Seiji Yamaguchi, Morihiro Ito, Seine A. Shintani, Takashi Nakamura, Hiroaki Takadama
On-Site Speaker (Planned) Seiji Yamaguchi
Abstract Scope The demand for prevention of infection as well as faster bone bonding is sharply increasing in orthopaedic and dental implants. In this study, conventional NaOH solution and heat treatment that allows Ti and its alloys bond to living bone was modified to induce calcium and iodine ions into the metal surfaces. As a result, iodine-containing calcium titanate with the 7.3 – 10.3 % of iodine was produced on the metals. The treated metals formed bone-like apatite in a simulated body fluid within 3 days, and exhibited high antibacterial activity against to methicillin-resistant Staphylococcus aureus, Staphylococcus aureus, and Escherichia coli (more than 99% reduction) without any cytotoxicity. This high reduction rate of bacteria almost maintained even if the treated Ti had been preserved under simulated body environment for a long period of half year (97.3% reduction). The treated metals with iodine-containing calcium titanate should be useful for orthopaedic and dental implants.

OTHER PAPERS PLANNED FOR THIS SYMPOSIUM

A Comparative Study of Protein Adsorption on Different Bio-surfaces for Osteointegration
Controlled Surface Topography of Titanium-based Implants via Use of Gas/Solid Reactions
Introductory Comments: Surface Treatments and Properties of Titanium and Titanium Alloys:
Sustainable Antibacterial Activity of Iodine-loaded Bioactive Titanium Metal by Chemical and Heat Treatment

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