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Meeting 2020 TMS Annual Meeting & Exhibition
Symposium Biodegradable Materials for Medical Applications II
Presentation Title Hydrogen Sensors for Noninvasively Monitoring the Status of Bioresorbable Magnesium Implants
Author(s) William Heineman, Daoli Zhao
On-Site Speaker (Planned) William Heineman
Abstract Scope Bioresorbable magnesium offers advantages over permanent stainless steel for implants such as plates and screws that are used for repairing damaged bone. Magnesium bioresorbs by reacting with water to form hydrogen gas, magnesium ion, and hydroxide ion. Hydrogen has proven to be especially useful for monitoring magnesium biodegradation during in vivo evaluation of Mg alloys and devices implanted in test animals because the hydrogen gas generated during bioresorption rapidly permeates through biological tissue. Both electrochemical and visual sensors that are sufficiently sensitive to measure the very low levels of hydrogen involved have been developed for this application. Monitoring hydrogen is easily done by placing the sensor on the skin above the implant where it responds to the hydrogen gas permeating through the skin. This simple, non-invasive procedure is potentially useful for point-of-care applications such as doctor’s office surgery follow-ups to check the corrosion status of implants in patients.
Proceedings Inclusion? Planned: Supplemental Proceedings volume

OTHER PAPERS PLANNED FOR THIS SYMPOSIUM

3D-printed Nanocomposites for Bone Repair
Additive Manufacturing of Biodegradable Fe-alloys for Orthopedic Applications
Advances in Zinc and its Alloys as Biodgradable Metals for Medical Applications
An Mg-Zn-Ca-based Alloy and a Biocompatible Ceramic Coating Towards Resorbable Bone Fixation Devices
Are those Biproducts of Bidegradable Metals Deleterious to Bone Healing?
B-10: New Approach in Development of Biodegradable FeMn Alloys
B-11: Novel Method for Increasing Mechanical Properties of Biodegradable Zinc
B-12: Research on Zn-Ag-Mg Alloy as a Potential Biodegradable Implant Material
B-1: Bilayer Coated Magnesium Weaves as Degradable Bio-scaffolds
B-3: Deformation Localization of Zn-Cu-Mn-Mg Alloys Designed for Bioresorbable Medical Implants
B-4: Discovery of Alloying Elements and Processing Parameters that Impart Improved Biocompatibility of Zinc-based Medical Implants
B-6: Evaluation of Electrospinning Parameters for Fabrication of Biodegradable Drug Carrier Silk Fibers
B-8: Long Term Inflammatory Response to Zinc Materials in Murine Arteries
B-9: Mechanical and Wear Behaviour of Mg-Ca Alloys for Orthopaedic Implant Applications
Biocompatibility Study of Luminescent Hydroxyapatite
Biodegradable Magnesium Implants – From Alloy Development to In Vivo Testing
Ceramic Composites as Bone Tissue Scaffolds
Corrosion Products of Zinc Implant Degradation Suppress Neointimal Hyperplasia
Different Approaches to Achieving the Appropriate Biodegradability for the Fe-Mn Alloy
Effect of Secondary Processing on Microstructure, Mechanical and Corrosion Response of a Biodegradable Mg1Zn2Ca Alloy
Fe-based Alloys with Extreme Properties for Thinner Absorbable Devices
Fixing Broken Hearts: Biodegradable Cardiovascular Implants
High Strength Rare Earth Free Mg Alloys with Controlled Degradation Behavior Through Microstructural Manipulation
Hydrogen Sensors for Noninvasively Monitoring the Status of Bioresorbable Magnesium Implants
In-vitro Corrosion and Mechanical Performance of Mg Alloy WE43 Processed by Spark Plasma Sintering
In-Vivo and In-Vitro Performance of Bioabsorbable BioMg 250 Mg Alloy Implants
Influence of Solution Heat Treatment on Microstructure, Hardness and Corrosion Behavior of Extruded RESOLOY
Low Pressure and Atmospheric Plasma-based Surface Modifications for Biodegradable Materials and Implants
Microstructure and Biodegradation Behavior of Additively Manufactured Magnesium
Non Invasive Degradation Tracking of Mg Implants in Humans
Novel Zn-Fe Matrix Nanocomposite as Biodegradable Material
On Contributors to Fracture in Absorbable Metals
Proteins and Flow Conditions: How They Influence the Degradation of Mg
Surface Engineering on Zinc for Better Biocompatibility
Synthesis of Absorable and Non-absorbable Sutures for Surgical Incisions and Wounds
Tailoring Degradation Behavior of Mg-5Nd Alloy by Intermetallic Distribution
Thermal Treatment of Zn-based Alloys for Vascular Stenting – Effect of Microstructure on Degradation Behavior and In-vivo Response

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