| About this Abstract |
| Meeting |
Materials Science & Technology 2020
|
| Symposium
|
Additive Manufacturing: Microstructure and Material Properties of Titanium-based Materials
|
| Presentation Title |
Influence of Different Post-printing Treatments on the In Vitro Biocompatibility of 3D Generated Titanium Plates |
| Author(s) |
Jakob Schneider, Elena Lopez, Frank Brueckner, Christoph Leyens, Ute Botzenhart, Bernhard Weiland, Kiriaki Katerina Papadopoulos, Andreas Schroeder |
| On-Site Speaker (Planned) |
Elena Lopez |
| Abstract Scope |
Patient-individual bone plates from TiAl4V ELI can be 3D-printed. Directly after printing the samples have a very rough surface requiring further processing. The aim of this study was to analyse the effect of different grinding procedures on sample surface and in vitro biocompatibility, to make sure, that the clinically approved material properties of the Ti-alloy are satisfactory. Initial average surface roughness of 3D-printed titanium discs, produced by SLM was reduced by sandblasting followed by barrel finishing, electro-polishing or plasma-polishing and was then evaluated using tactile surface quality measurement. Biocompatibility of the different samples was assessed by quantification of metal-ion release, indirect cell viability and cytotoxicity tests as well as direct cell adhesion, analysed by fluorescence and SEM. Mouse fibroblasts, osteosarcoma cells, human primary gingival fibroblast as well as human gingival epithelial cells were used in this study. Statistical evaluation was performed by Kruskal Wallis test, followed by posthoc Dunnīs test. |