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Meeting 2026 TMS Annual Meeting & Exhibition
Symposium Advanced Biomaterials and Implants
Presentation Title A-4: Novel Ultrasonic Melt Shearing Processing for Bioactive Magnesium-Based Metal Matrix Nanocomposites
Author(s) Andres Larraza, David Jensen, Shane Burke, Sun Latt, Pedram Sotoudehbagha, Mehdi Razavi
On-Site Speaker (Planned) Andres Larraza
Abstract Scope Most standard biocompatible metals consist of either titanium or stainless steel. These materials have high mechanical strength and are bioinert, which allows for long-term implantation with low risks of immune response. Implants composed of these alloys do not improve the healing time of bone defects. Novel biomaterials focus on biodegradable and bioactive materials that improve the healing of bone wounds. Previously, we described a magnesium-based metal matrix nanocomposite (MNC) that incorporates scandium and strontium into the matrix for improved bioactivity, as well as a bioactive glass-ceramic. This MNC showed improvements in mechanical and electrochemical behavior. We present a novel metal processing method that incorporates ultrasonic melt stimulation with melt shearing to homogenize the melt while deagglomerating glass ceramics and reduce structural defects by microstructure refinement and degassing via cavitation. We have analyzed the effects of melt processing on microstructure, corrosion, and mechanical behavior of various processed MNCs compared with WE43.
Proceedings Inclusion? Planned:
Keywords Magnesium, Biomaterials, Composites

OTHER PAPERS PLANNED FOR THIS SYMPOSIUM

A-1: Additively Manufactured Radially Graded Stainless Steel Lattices for Osseointegrative Applications
A-21: 3D Printing of Trabecular Mimicking Bone Scaffolds with a Focus on Accessibility in a Clinical Setting
A-2: Development and Characterization of MAO-Treated High-Entropy Alloy for Potential Application in the Biomedical Field
A-3: Laser Surface Alloying of Ti-20Nb-6Ta with Cu and Ag: Microstructural Formation, Corrosion Behavior, and Antibacterial Performance
A-4: Novel Ultrasonic Melt Shearing Processing for Bioactive Magnesium-Based Metal Matrix Nanocomposites
A-5: Patient-Specific Implant Evaluation in Osteosarcoma Using Machine Learning
A-6: Situ Investigation of Degradation and Crack Propagation in Mg-Zn-Ca Biodegradable Alloys
A-7: Spinodal Zirconium Alloys with Exceptional Biomechanical Compatibility and Low Magnetic Susceptibility for Orthopedic Implants
A Bioengineered Tubular Scaffold Platform for in Vitro Modeling of Renal Proximal Tubule Structure and Function
Additive Manufacturing of Fe-AZ31 Immiscible Bimetallic Composites for Degradable Implants
An Investigation of Hydrogel-Based Drug Delivery Methods to Enhance Introduction of Timolol Maleate for Ocular Treatment
Anti-Calcification Property of Sulfur Functional Group Using Low Temperature Plasma on Polymeric Scaffolds
Approaches for Microneedle Delivery of Drugs with Poor Water Solubility
Bio-Integrative, Fiber-Reinforced Fixation Device in Carpometacarpal (CMC) Joint Fusions Following Carpal Boss Removal: A Case Series
Biodegradable Brain Pressure Sensor
Biodegradable Hybrid Materials for Minimally Invasive Implantable Devices
Biomimetic Scaffolds for Anterior Cruciate Ligament (ACL) Repair
Biomimetic Surface Modification of Titanium Implants to Mitigate Antibacterial Efficacy and Enhance Cell Functionality
Comparative Evaluation of Cu and Zn Nanopowder-Mixed EDM on Ti-6Al-4V for Orthopedic Implant Applications
Design and Characterization of Biocompatible Nanostructured Electrodes for Enhanced Neural Signal Acquisition
Early Cell Response to Graphene and Hydroxyapatite-Based Coatings on Ti-6Al-4V for Dental Implant Applications
Eliminating Implant Failure in Humans with Nano Chemistry: 30,000 Cases and Counting
Engineering of Drug-Eluting Microparticle-Loaded Hydrogel for Targeted Immunotherapy of Cancer
Genipin-Crosslinked Shear-Thinning Nanoclay/Iohexol/Alginate Gel for Image-Guided Embolization
Gold CMU Array: 3D Nanoprinted Gold Microelectrodes on Flexible Substrates
High-Strength Low-Degradation Mg Microtubes for Biodegradable Vascular Stents
Improvement of Mechanical Properties and Wettability of 5Y-TZP by Change Compaction Pressure and Heating Rate During Sintering
In- Omnidirectionally Stretchable, Biodegradable Mesh Electrode with Re-Entrant Structure for Spatial-Stable Functional Position on Dynamic Organs
In-Vitro Response and Raman Characterization of Helically Coiled Electrospun Fibers for Cardiac Patch
In Vivo Degradation Pathways of Mg-10Gd Biodegradable Implants Revealed by Atom Probe Tomography
Influences of the Oxide Dispersoids on Microstructural Evolution and Biocompatibility of Ti-6Al-4V Alloy
Interplay of Wear and Corrosive Processes in Tribocorrosion: Factors of Volume Loss, Metal Release, and Oxide Formation
Maxillary Bone Strain During Dental Implant Insertion
Phase Engineering of Mg-Zn Alloy for Bioimplantable Electronics
Preliminary Analysis of Material Degradation and Residue Retention on a Reusable Orthopedic Awl: A Case Study
Understanding Tribological Stability in Porous Ti-Nb-Mo Alloys for Biomedical Use

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