About this Abstract |
| Meeting |
2026 TMS Annual Meeting & Exhibition
|
| Symposium
|
Biological Materials Science
|
| Presentation Title |
Efficient and Conformal Electrospray Deposition of Bioactive Payloads |
| Author(s) |
Jonathan Phillip Singer |
| On-Site Speaker (Planned) |
Jonathan Phillip Singer |
| Abstract Scope |
Electrospray deposition (ESD) is a spray coating process that utilizes a high voltage to atomize a flowing solution into charged microdroplets. These self-repulsive droplets evaporate as they travel to a target grounded substrate, depositing the solution solids as thin films. These thin films can be utilized in a variety of biomedical applications. Our recent work has established ESD as a viable alternative to other traditional methods of thin films as it inherently limits materials waste, capable of achieving deposition efficiencies nearing 100%. We have further shown that DNA vaccine coated microneedle arrays (MNAs) are capable of eliciting antigen response in an in vivo rat model comparable to traditional injection. Here, we discuss this work along with our efforts to incorporate additional sensitive bioactive materials into the efficient modes of ESD, where high surface charge and electrostatic shear can damage the secondary structure necessary for activity. |
| Proceedings Inclusion? |
Planned: |
| Keywords |
Biomaterials, Surface Modification and Coatings, Composites |