About this Abstract |
| Meeting |
2026 TMS Annual Meeting & Exhibition
|
| Symposium
|
Biological Materials Science
|
| Presentation Title |
Mechanical Characterization of Col1a1+/- Osteogenesis Imperfecta Type I Bone |
| Author(s) |
Hanwen Fan, Yuxiao Zhou |
| On-Site Speaker (Planned) |
Hanwen Fan |
| Abstract Scope |
Osteogenesis imperfecta (OI) is a genetic disorder caused by mutations in type I collagen that leads to fragile bones. However, the correlation between genetic mutation and bone fragility at macro-scale is not well understood. This study examined how pathological alterations in microstructure and composition in OI bones impair bone mechanical strength. |
| Proceedings Inclusion? |
Planned: |