About this Abstract |
| Meeting |
2026 TMS Annual Meeting & Exhibition
|
| Symposium
|
Biomaterials for 3D Printing of Scaffolds & Porous Materials
|
| Presentation Title |
3-Dimensional Electrocatalytic On-Site Oxygenation using Aerosol Jet Printing for Implanted Cell Therapies |
| Author(s) |
Aaditya Nandakumar, Rahul Panat, Itzhaq Cohen-Karni |
| On-Site Speaker (Planned) |
Rahul Panat |
| Abstract Scope |
Implantable cell-based therapies are limited by the scarcity of oxygen owing to its poor diffusivity in the absence of vasculature. Previous oxygenation approaches such as using metal peroxides provides transient oxygenation capable of supporting low cell density, while subcutaneous oxygen delivery requires extensive maintenance from the patient. Additionally, scaling up such methods to accommodate the necessary number of cells for humans would result in impractically sized devices for implantation. Long-term oxygenation support of high cell densities has eluded cell therapy. Electrocatalytic oxygenation has demonstrated sustained cell function with an unlimited oxygen supply. Here we show a 3D printed electrocatalytic device for implanted cell therapies, fabricated using aerosol jet printing (AJP).
AJP is an additive manufacturing technique capable of fabricating 3D structures using a variety of materials. A 3D oxygen-generating structure exhibits an enhanced oxygenation volume compared to planar devices, which can be used to support high cell density implanted devices. |
| Proceedings Inclusion? |
Planned: |
| Keywords |
Additive Manufacturing, Biomaterials, |