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Meeting MS&T25: Materials Science & Technology
Symposium 3D Printing of Biomaterials and Devices
Presentation Title C-3: In Vivo Performance of Additive Manufacturing Implants vs. Commercially Available Implants
Author(s) Mari Koike, Azusa Seki, Yutaka Yanaba, Susan K Hummel, Toru Okabe
On-Site Speaker (Planned) Mari Koike
Abstract Scope The objective of this study was to evaluate in vivo performance of additive manufacturing (AM) implants compared to a commercially available SETiO®Plus implant. The AM implants were fabricated using Ti6Al4V ELI alloy powder, with and without lattice structures, matching the same overall geometry of SETiO®Plus implants (3.0 mm/diameter, 8.0 mm/length). Specimens from each implant type (n=4/type) were placed in the femurs of 3 rabbits and retrieved after six weeks. A push-out test and histological analysis were performed. The data were analyzed using one-way ANOVA followed by Tukey’s test (α=0.05). The push-out tests showed that the shar stiffness of AM implants with lattice structure and SETiO®Plus implants tended to be higher than that of AM implants without lattice structure. Histological analyses indicated osseointegration without inflammatory responses surrounding bone with all the type of implants. AM technology will be a promising method to fabricate customized porous implants in the future.

OTHER PAPERS PLANNED FOR THIS SYMPOSIUM

3D Printed Ceramics in Natural Medicine Delivery for Bone Regeneration
3D Printing of Active Medical Devices for Transdermal Drug Delivery and Biosensing
A Collagen-Based Bioink for 3D Printing Biomimetic Tissue Graft for Rotator Cuff Repair
Bioglass Reinforced Ti6Al4V Composites for Load-Bearing Implants
Biomechanical Tuning of Composites for Tissue Engineering
C-1: Alkali-Heat Treated Titanium Loaded with Curcumin for Bone Tissue Engineering; Release Kinetics and In Vitro Biological Properties
C-2: Copper-Based Antimicrobial Filters Fabricated via a Hybrid 3D Printing–Casting Approach
C-3: In Vivo Performance of Additive Manufacturing Implants vs. Commercially Available Implants
Engineering Location, External Shape, and Internal Pore Geometry, to Achieve Stiffness-Matched, 3D Printed, Nickel-Titanium Mandibular Graft Fixation Plates
Fabrication of Personalized Resorbable Polymer Textile Scaffolds Using a Multi-Axis and Multi-Modality Biofabrication Platform
Virtual Surgical Planning for the Design and Manufacturing of Stiffness-Matched Personalized Load-Bearing Implants: Transfemoral Percutaneous Implant Case

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