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Meeting MS&T24: Materials Science & Technology
Symposium Society for Biomaterials: Biomaterial Applications
Presentation Title Evaluating Impact of Particle Size and Loading on Echogenicity of Medical Devices
Author(s) Samuel Vibostok, Abby Whittington
On-Site Speaker (Planned) Samuel Vibostok
Abstract Scope Peripherally Inserted Central Catheters (PICC) are thin, flexible tubes that provide fluids and drugs to areas of the body where intravenous access has become difficult. Without X-ray fluoroscopy to guide the PICC in real time, physicians have difficulty placing the PICCs at the patient’s bedside, resulting in malpositioning incidents in 10-85% of insertions. Ultrasound has been sought as a potential alternative, but signals weaken drastically at small sizes, making PICCs difficult to locate. Adding a more echogenic material into the catheters can increase the overall signal. We have been developing polyurethane composites loaded with several different particles, including hydroxyapatite and clay, with the goal of improving echogenicity without compromising mechanical performance. We aim to determine the optimal particle size and loading that maximizes echogenicity, using SEM, DSC and ultrasound to confirm results. Initial results show minimal increase in signal-to-noise, indicating a limited echogenic boost from the particles.

OTHER PAPERS PLANNED FOR THIS SYMPOSIUM

3D Bioprinting Human Tissues and the Path Towards Translation
A Coordination-Crosslinked Degradable Elastomer
C-13: Mechanical Properties of 3D Printed Dental Resins in Different Orientations
C-14: Multifunctional Magnetite Superparamagnetic Nanoparticles
Evaluating Impact of Particle Size and Loading on Echogenicity of Medical Devices
Fine-Tuning Iron Nanoparticles Sizes Using Long Alkyl Chained Surfactants for Magnetic Particle Imaging Applications
Mimicking Tumors as a S.M.A.R.T.E.R. Way to Treat Transplant Rejection and Inflammatory Diseases
Novel Decellularized, Dehydrated Human Placental Extracellular Matrix (ECM) Mineral Composite for Bone Applications
Scalable, Green Thiol-Norbornene Photopolymers for 3D Printing of Biomaterials
Thermally Responsive Microswimmers Biomanufactured by Genetically Engineered Probiotics for Antibiofilm Therapies
Titania Nanorods for Posterior Dental Restoration Composites

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