About this Abstract |
| Meeting |
MS&T26: Materials Science & Technology
|
| Symposium
|
3D Printing of Biomaterials and Devices
|
| Presentation Title |
Physicochemical Evaluation and Cytocompatibility of 3D Printed 1393-Borate Bioglass Composite |
| Author(s) |
Dipanjan Ash, Kaushik Sarkar |
| On-Site Speaker (Planned) |
Dipanjan Ash |
| Abstract Scope |
Borate-based bioactive glasses achieve higher conversion to hydroxyapatite than silicate glasses but are often characterized by rapid degradation and low mechanical properties. 1393-borate glass was synthesized by sol-gel process and evaluated using XRD, SEM and particle size analyzer. Addition of 2-10wt% of bioceramics shows improvement in the physical and mechanical properties of 1393B. Extrusion based 3D printing was used to prepare 5wt% bioceramic incorporated 1393B glass porous scaffolds. Printing parameters were optimized after checking the morphological features and mechanical strength of the sintered samples. Macroporous (150-200µm) scaffold was prepared and found to be ~50% degradable after 28 days of immersion in SBF. SEM analysis showed that the glassy phase is more degradable than the ceramic phase in the composite. The cell culture results indicate that the samples are cytocompatible and support cell attachment and proliferation. Morphological analysis found that the cells are well attached and spread on the samples. |