About this Abstract |
| Meeting |
2027 TMS Annual Meeting & Exhibition
|
| Symposium
|
Advanced Biomaterials and Implants
|
| Presentation Title |
Noise-tolerant biodegradable wireless sensing for accurate intracranial pressure measurement |
| Author(s) |
Minki Hong, Seunghun Han, Jahyun Koo |
| On-Site Speaker (Planned) |
Minki Hong |
| Abstract Scope |
Long-term intracranial pressure (ICP) monitoring is essential for managing neurological disorders, but conventional sensors often suffer from signal instability during chronic use. Physiological motion, environmental interference, and sensor drift can distort pressure readouts and reduce measurement accuracy. Here, we developed a biodegradable wireless ICP sensing system designed to improve reliability by suppressing unwanted signal fluctuations. The platform was evaluated in vitro under disease-mimicking conditions and further validated in multiple in vivo models. In rabbits, the system continuously detected ICP changes induced by repeated abdominal compression for over four weeks, showing trends comparable to a commercial pressure sensor. It also monitored pressure elevation after autologous blood-induced intracranial hemorrhage and pressure reduction following mannitol treatment. In a kaolin-induced porcine hydrocephalus model, the device enabled wireless real-time ICP tracking over an extended period. These results demonstrate the potential of noise-tolerant biodegradable wireless sensing for stable long-term ICP monitoring. |
| Proceedings Inclusion? |
Planned: |
| Keywords |
Biomaterials, Electronic Materials, Environmental Effects |