About this Abstract |
| Meeting |
MS&T25: Materials Science & Technology
|
| Symposium
|
3D Printing of Biomaterials and Devices
|
| Presentation Title |
Fabrication of Personalized Resorbable Polymer Textile Scaffolds Using a Multi-Axis and Multi-Modality Biofabrication Platform |
| Author(s) |
Javier Vazquez-Armendariz, Tanya Djemal, Jordan Peiffer, Evan Gilligan, Ciro A. Rodriguez, David Dean |
| On-Site Speaker (Planned) |
Javier Vazquez-Armendariz |
| Abstract Scope |
In the pursuit of fabricating polymer textile scaffolds for regenerative medicine, several fiber deposition techniques have been studied. However, a single forming technique may be insufficient to meet the mechanical and biological requirements for a tissue engineering device. The fabrication of geometries that better conform to the anatomy of the target tissue is often neglected due to the inability of current techniques to fabricate non-planar textiles. In this work we present the integration of Melt Electrowriting and Fused Deposition Modeling to deposit textiles on curving surfaces and to incorporate cell-bearing hydrogel sheets that are strong enough to support suturing, have a balanced microstructure in fiber and pore size that is suitable for cell proliferation and vascularization, and which feature personalized out-of-plane, form-fitting geometries produced by using multi-axis kinematics. This “hybridization” of techniques in a single printer is currently being applied for the fabrication of personalized bone and corneal implants. |