About this Abstract |
| Meeting |
2026 TMS Annual Meeting & Exhibition
|
| Symposium
|
Biomaterials for 3D Printing of Scaffolds & Porous Materials
|
| Presentation Title |
3D Hybrid Bioprinting of Muscle Tissue Integrating Acoustic Cell Patterning and Microextrusion |
| Author(s) |
Md Shahriar, Marielena Molinares Ponce, Changxue Xu |
| On-Site Speaker (Planned) |
Md Shahriar |
| Abstract Scope |
Precise control of cell alignment is essential for replicating the intricate architecture of tissues. In the native microenvironment, cell distribution and patterning are critical components for functionality. In this study, we present an integrated acoustic-assisted extrusion bioprinting platform that enables real time and contactless alignment of muscle cells. A customized nozzle head for 3D printing based on PZT transducer attached to an acrylic rod has been used to generate acoustic waves within a microchannel, aligning cells along pressure nodes prior to extrusion. With bioink formulations that include GelMA and sodium alginate, the continuous stacking of extruded and crosslinked layers of aligned myoblasts for 3D bioprinting has been achieved. The system is modular and compatible with printers in the market, offering a low-cost tool to control the native-like organization while bioprinting tissues such as muscle, cartilage, and nerve. |
| Proceedings Inclusion? |
Planned: |
| Keywords |
Additive Manufacturing, Biomaterials, |