| Abstract Scope |
Healthcare, in general, and orthopaedics and bone treatments, more specifically, are a few of the crucial fields that 3D printing has revolutionised. Trying to answer the demand for more affordable and personalised treatments for osteopathic patients, the AffordBoneS project aims to explore the field of bone regeneration and offer customised and low-cost solutions for bone augmentation. The solution is to treat patients with biomimetic 3D scaffolds based on calcium phosphate (CaP) multi-substituted with strontium, magnesium, and zinc ions fabricated via ceramic vat photopolymerization. The impact of the selected trace elements and the sintering temperature was investigated in relation to the obtained crystalline phase content, microstructure, elemental distribution, thermal stability, mechanical properties and osteoclast activity on the surface. Detailed in vitro biological characterization was conducted to determine the scaffold's osteogenic properties and the effect of the microstructure and ions on bone regeneration. |