| Abstract Scope |
Coronary and peripheral artery diseases, like atherosclerosis, result from narrowed blood vessels due to fat or calcium deposits, hindering blood flow. Stents, often used with angioplasty, help increase vessel diameter and restore circulation. Bare metal stents provide mechanical support, while polymer-coated drug-eluting stents offer molecular therapy but may lead to long-term complications such as inflammation, thrombosis, and restenosis. To address these issues, bioresorbable stents have been developed. Made from materials that corrode and are absorbed by the body, these stents function as scaffolds for 4-6 months before breaking down, allowing arteries to regain normal function without permanent implants. This presentation will review zinc-based bioresorbable materials for stenting, comparing their mechanical properties and behavior in vascular environments to other metals like magnesium and iron, and will discuss challenges in creating high-strength, biocompatible zinc materials and the corrosion products from in vivo degradation. |