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Meeting 2026 TMS Annual Meeting & Exhibition
Symposium Accelerated Discovery and Insertion of Next Generation Structural Materials
Presentation Title Accelerating W-Alloy Design with Physics-Guided Machine Learning
Author(s) Prashant Singh, Sai Pranav Reddy Guduru, Sougata Roy, Mkpe O. Kekung, Ryan Ott, Duane D Johnson, Luke E Gaydos, Hailong Huong, Gaoyuan Ouyang, Andrew Kustas
On-Site Speaker (Planned) Prashant Singh
Abstract Scope The stability of tungsten-based structural alloys under extreme conditions is critical to the reliability of plasma-facing components in fusion reactors such as ITER and DEMO. However, tungsten’s inherently high ductile-to-brittle transition temperature (DBTT), irradiation-induced hardening, and neutron driven transmutation significantly constrain its long-term performance. This work presents a physics informed machine learning (ML) framework to accelerate the discovery of W-rich alloys with enhanced mechanical resilience and radiation tolerance. By integrating data from density functional theory (DFT) and thermodynamic modeling (CALPHAD), the ML models learn complex composition–structure property relationships that govern strength–ductility trade-offs and defect evolution under irradiation. This framework enables rapid screening of alloy chemistries optimized for improved room-temperature ductility, reduced DBTT, and greater radiation resistance, while maintaining thermal stability. Predictions are validated using electronic-structure calculations and available experimental data. Embedding physics-based priors into ML ensures interpretable, robust property predictions, advancing multiscale alloy design for extreme fusion energy environments.
Proceedings Inclusion? Planned:
Keywords High-Temperature Materials, Modeling and Simulation, Machine Learning

OTHER PAPERS PLANNED FOR THIS SYMPOSIUM

A Combinatorial Approach for the Development of Ternary Alloys
Accelerated Discovery of Additively Manufacturable Al-Zr-Er-Ni Alloys with Enhanced Strength and Ductility Via CALPHAD-Based ICME Technique
Accelerated Mapping of Metallurgical Impact Bonding of GRX 810 Nickel ODS AM Alloys Using Laser Induced Particle Impact Testing (LIPIT)
Accelerating W-Alloy Design with Physics-Guided Machine Learning
AlloyBot: An Automatic Arc-Melting System for High-Throughput Alloy Synthesis
Automated High-Throughput Characterization of Structural Materials for Extreme Environments
CALPHAD Based Screening for Rapid Training of Alloy Design Models
Coupled Design and Characterization Tools to Enable Components with Spatially Varying Materials and Properties
DARPA METALS: Introducing New Material Test Methods and Design Optimization Paradigms for Future Multi-Material Structures
E-44: Evaluating Elemental Powder-Based Direct Energy Deposition for High-Throughput Synthesis of Alloys
Generative Design of Compositionally Graded Turbine Rotors
Hydrogen Embrittlement Behavior of Ni-Based Alloy Fabricated by Laser-Powder Bed Fusion
Leveraging Domain Knowledge for Optimal Initialization in Materials Optimization Frameworks
Machine-Learning Prediction of Yield Strength for W-Ta-Nb Alloy from Room Temperature to 2000°C
Machine Learning Domain Knowledge-Based Design of Alloys with High Strength
Microstructural Evolution During Processing and Creep of Re-Free Single Crystal Superalloy ERBO/15
Multimaterial Structures: Materials, Test Methods, Models and Data Enabled Topology Optimized Design
New Insights into the Evolution of Powder Metallurgy (PM) Ni-Based Superalloys During Consolidation and Thermomechanical Processing
Novel Approach to Rapid Material Characterization and Multi-Material Design Optimization
On the Effect of Temperature Cycling and Stress on the Formation of σ-Phase in Single Crystal Superalloys
RADICAL: Rapid Array DImple-Based Co-Design of Gradient MateriaL and Geometry
Rapid and Flexible Design of Alloys Using The Alloy Optimization Software (TAOS)
Rapid Exploration of Al-Ti-Fe-Si Alloys Via Automated High-Throughput Laboratory X-Ray Diffraction (XRD) and Fluorescence Analysis (XRF)
Simultaneous Design and Discovery of Functionally-Graded Alloys, Supported by Material Informatics and Rapid Testing
SMART: Novel Material Library Synthesis to Accelerate Structural Alloy Discovery
Success and Challenges with Qualifying 6061-RAM2 and 7050-RAM2 Aluminum Alloys for LBPF Additive Manufacturing
"Old-Fashioned" Cast & Wrought Ni-Base Superalloys - Some Remaining Challenges for Alloy and Process Design

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