About this Abstract |
| Meeting |
2027 TMS Annual Meeting & Exhibition
|
| Symposium
|
3D Printing of Scaffolds and Porous Materials
|
| Presentation Title |
Development and Characterization of a Photocurable Conductive Hydrogel for Cardiac Tissue Engineering via Vat Photopolymerization |
| Author(s) |
Polette Esmeralda Cortez, Robert Pankow, Carlos Cabrera Martínez |
| On-Site Speaker (Planned) |
Polette Esmeralda Cortez |
| Abstract Scope |
Cardiovascular disease remains the leading cause of death worldwide, with myocardial infarction (MI) representing one of its most significant causes. Because adult cardiac tissue possesses limited regenerative capacity, heart transplantation remains the only definitive treatment for end-stage heart failure, despite limited donor availability and the risk of immune rejection. Tissue engineering and additive manufacturing offer promising alternatives for cardiac regeneration. In particular, vat photopolymerization enables the fabrication of hydrogel scaffolds with precise geometries that better mimic native extracellular matrix architecture. This work investigates the synthesis, characterization, and printability of a photocurable electroconductive PEGDA-PEDOT:PSS hydrogel for cardiac tissue engineering. The hydrogel’s mechanical and electrically conductive properties are first characterized using mold-cast, photocrosslinked samples and subsequently evaluated following fabrication by vat photopolymerization. Bioactive cues are incorporated to support AC16 cardiomyocyte adhesion and growth. The findings of this study provide a foundation for the future biofabrication of electroactive cardiac scaffolds. |
| Proceedings Inclusion? |
Planned: None Selected |
| Keywords |
Biomaterials, Additive Manufacturing, Characterization |