About this Abstract |
| Meeting |
MS&T24: Materials Science & Technology
|
| Symposium
|
Society for Biomaterials: Biomaterial Applications
|
| Presentation Title |
Fine-Tuning Iron Nanoparticles Sizes Using Long Alkyl Chained Surfactants for Magnetic Particle Imaging Applications |
| Author(s) |
Aleia Williams, Lu Liu, Charles Johnson, Jacqueline Johnson |
| On-Site Speaker (Planned) |
Aleia Williams |
| Abstract Scope |
Magnetic particle imaging (MPI) is a noninvasive medical imaging technique created in the early 2000s by Gleich and Weizenecker that provides real-time, high-resolution images by directly detecting superparamagnetic iron oxide nanoparticles in the body. Since signal detection in MPI is highly dependent on the nanoparticle’s properties, magnetic tracer development is a central research area for improving MPI capabilities. Standard MPI tracers include 25-30 nm iron oxide nanoparticles, but further improvement of tracers can be achieved by developing pure iron nanoparticles. However, it is difficult to synthesize iron nanoparticles above 15 nm due to risk of agglomerations. Therefore, this study investigates a simple, one-pot synthesis for creating larger iron nanoparticles between 18-25 nm through thermal decomposition of iron pentacarbonyl. Fine-tuning of different nanoparticle sizes was achieved by using different lengths of alkyl chained surfactants. It was found that longer alkyl chained surfactants allowed for larger iron nanoparticle growth without agglomeration. |