| Abstract Scope |
Airway biomechanics, including airflow, stent deformation, and tissue compression, are important biomarkers for assessing airway remodeling and disease progression in patients with central airway obstruction. Here, we present a multifunctional bioelectronic airway stent integrating distributed flexible sensors with programmable magnetic materials for fully wireless monitoring of airflow and airway biomechanics. It combines soft bioelectronic materials, flexible electronics, and reconfigurable magnetic structures to continuously measure airflow, stent deformation, and tissue compression wirelessly. By remotely programming embedded magnetic markers, the sensing range and sensitivity can be dynamically reconfigured in situ to adapt to dynamic environments. The distributed sensing architecture provides spatially resolved measurements of airway biomechanics, while machine-learning models correlate wireless sensor signals with airflow, deformation, and tissue compression. This work demonstrates how programmable magnetic materials and implantable bioelectronics can be integrated into intelligent biomaterials for adaptive sensing and establishes a versatile platform for long-term physiological monitoring and next-generation implantable medical devices. |