About this Abstract |
| Meeting |
2026 TMS Annual Meeting & Exhibition
|
| Symposium
|
Advanced Biomaterials and Implants
|
| Presentation Title |
In Vivo Degradation Pathways of Mg-10Gd Biodegradable Implants Revealed by Atom Probe Tomography |
| Author(s) |
Selase Torkornoo |
| On-Site Speaker (Planned) |
Selase Torkornoo |
| Abstract Scope |
Recent advances in magnesium (Mg)-based alloys have focused on controlling their degradation behavior for potential use as bioresorbable implants in orthopedic applications. However, current analytical techniques lack the resolution to clearly map Mg ion diffusion pathways and distribution within the complex architecture of bone tissue. To address this limitation, a quantitative compositional analysis was performed to assess Mg distribution both near and distant from the implant site. Mg-10 wt.% Gd (Mg-10Gd) alloy implants were placed in rat tibiae for 18 weeks, and degradation behavior and surrounding bone structure were investigated using electron microscopy and atom probe tomography. Results revealed pronounced Mg enrichment in the intercrystalline regions of hydroxyapatite, with a clear compositional gradient increasing toward the implant interface. These findings provide novel atomic-scale insights into Mg ion diffusion during implant degradation and suggest that hydroxyapatite adapts structurally in response to localized Mg incorporation during bone remodeling. |
| Proceedings Inclusion? |
Planned: |
| Keywords |
Magnesium, Biomaterials, Characterization |