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Meeting 2026 TMS Annual Meeting & Exhibition
Symposium Advanced Biomaterials and Implants
Presentation Title Comparative Evaluation of Cu and Zn Nanopowder-Mixed EDM on Ti-6Al-4V for Orthopedic Implant Applications
Author(s) Alok Kumar, Abhishek Singh, Satish Jaiswal
On-Site Speaker (Planned) Alok Kumar
Abstract Scope This study evaluates the effects of Copper (Cu) nanopowders and Zinc (Zn) nanopowder-mixed dielectrics in Powder Mixed EDM (PMEDM) on the surface and biological performance of Ti-6Al-4V alloy for orthopedic implant applications. Results suggest, Zn-mixed dielectric yielded higher surface roughness (Ra = 2.8 µm) as compared to Cu (Ra = 2.4 µm), promoting better osteointegration and hardness increased to 430 HV (Cu) and 410 HV (Zn), while Cu-treated surfaces exhibited superior wear resistance (0.92 × 10⁻⁶ mm³/N•m) and lower corrosion current density (1.4 µA/cm²) compared to Zn (1.8 µA/cm²). However, In-vitro cytocompatibility tests showed higher cell viability on Zn-modified surfaces (~93%) in comparison to Cu (~87%). Surface analyses confirmed oxide and phosphate layer formation, enhancing bioactivity. Overall, Zn nanopowder emerges as the superior choice as an additive metallic powder in dielectric due to its balanced enhancement of both biological response as well as acceptable mechanical/corrosion performance, making it more suitable for orthopedic implants requiring biocompatibility and early-stage osseointegration.
Proceedings Inclusion? Planned:
Keywords Biomaterials, Titanium, Surface Modification and Coatings

OTHER PAPERS PLANNED FOR THIS SYMPOSIUM

A-1: Additively Manufactured Radially Graded Stainless Steel Lattices for Osseointegrative Applications
A-21: 3D Printing of Trabecular Mimicking Bone Scaffolds with a Focus on Accessibility in a Clinical Setting
A-2: Development and Characterization of MAO-Treated High-Entropy Alloy for Potential Application in the Biomedical Field
A-3: Laser Surface Alloying of Ti-20Nb-6Ta with Cu and Ag: Microstructural Formation, Corrosion Behavior, and Antibacterial Performance
A-4: Novel Ultrasonic Melt Shearing Processing for Bioactive Magnesium-Based Metal Matrix Nanocomposites
A-5: Patient-Specific Implant Evaluation in Osteosarcoma Using Machine Learning
A-6: Situ Investigation of Degradation and Crack Propagation in Mg-Zn-Ca Biodegradable Alloys
A-7: Spinodal Zirconium Alloys with Exceptional Biomechanical Compatibility and Low Magnetic Susceptibility for Orthopedic Implants
A Bioengineered Tubular Scaffold Platform for in Vitro Modeling of Renal Proximal Tubule Structure and Function
Additive Manufacturing of Fe-AZ31 Immiscible Bimetallic Composites for Degradable Implants
An Investigation of Hydrogel-Based Drug Delivery Methods to Enhance Introduction of Timolol Maleate for Ocular Treatment
Anti-Calcification Property of Sulfur Functional Group Using Low Temperature Plasma on Polymeric Scaffolds
Approaches for Microneedle Delivery of Drugs with Poor Water Solubility
Bio-Integrative, Fiber-Reinforced Fixation Device in Carpometacarpal (CMC) Joint Fusions Following Carpal Boss Removal: A Case Series
Biodegradable Brain Pressure Sensor
Biodegradable Hybrid Materials for Minimally Invasive Implantable Devices
Biomimetic Scaffolds for Anterior Cruciate Ligament (ACL) Repair
Biomimetic Surface Modification of Titanium Implants to Mitigate Antibacterial Efficacy and Enhance Cell Functionality
Comparative Evaluation of Cu and Zn Nanopowder-Mixed EDM on Ti-6Al-4V for Orthopedic Implant Applications
Design and Characterization of Biocompatible Nanostructured Electrodes for Enhanced Neural Signal Acquisition
Early Cell Response to Graphene and Hydroxyapatite-Based Coatings on Ti-6Al-4V for Dental Implant Applications
Eliminating Implant Failure in Humans with Nano Chemistry: 30,000 Cases and Counting
Engineering of Drug-Eluting Microparticle-Loaded Hydrogel for Targeted Immunotherapy of Cancer
Genipin-Crosslinked Shear-Thinning Nanoclay/Iohexol/Alginate Gel for Image-Guided Embolization
Gold CMU Array: 3D Nanoprinted Gold Microelectrodes on Flexible Substrates
High-Strength Low-Degradation Mg Microtubes for Biodegradable Vascular Stents
Improvement of Mechanical Properties and Wettability of 5Y-TZP by Change Compaction Pressure and Heating Rate During Sintering
In- Omnidirectionally Stretchable, Biodegradable Mesh Electrode with Re-Entrant Structure for Spatial-Stable Functional Position on Dynamic Organs
In-Vitro Response and Raman Characterization of Helically Coiled Electrospun Fibers for Cardiac Patch
In Vivo Degradation Pathways of Mg-10Gd Biodegradable Implants Revealed by Atom Probe Tomography
Influences of the Oxide Dispersoids on Microstructural Evolution and Biocompatibility of Ti-6Al-4V Alloy
Interplay of Wear and Corrosive Processes in Tribocorrosion: Factors of Volume Loss, Metal Release, and Oxide Formation
Maxillary Bone Strain During Dental Implant Insertion
Phase Engineering of Mg-Zn Alloy for Bioimplantable Electronics
Preliminary Analysis of Material Degradation and Residue Retention on a Reusable Orthopedic Awl: A Case Study
Understanding Tribological Stability in Porous Ti-Nb-Mo Alloys for Biomedical Use

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