About this Abstract |
| Meeting |
2027 TMS Annual Meeting & Exhibition
|
| Symposium
|
3D Printing of Scaffolds and Porous Materials
|
| Presentation Title |
Dispersion-Controlled High-Ceramic Functional Bioinks for Digital Light Processing of Bone Scaffolds |
| Author(s) |
Antrakrate Gupta, Rupita Ghosh, Ashok Kumar, Kantesh Balani, Shikhar K. Jha |
| On-Site Speaker (Planned) |
Antrakrate Gupta |
| Abstract Scope |
Functional bioinks for bone tissue engineering require ceramic loadings >10 wt.% while maintaining rheological and dispersion stability for digital light processing (DLP). Unlike structural ceramic DLP resins (>30 wt.%), functional bioinks are generally limited to ~10–20 wt.% by viscosity escalation (>3 Pa·s), optical scattering, and shear-induced phase separation. Here, we establish dispersion stability and shear recovery—not solid loading—as the governing materials design criteria for high-ceramic DLP bioinks. Using a solvent-free PEGDA platform, 58S bioglass bioinks containing up to 50 wt.% ceramic maintain DLP-compatible viscosities (1–2 Pa·s), 100% shear recovery, and negligible sedimentation during printing. Real-time computer vision analysis shows that the RuAn mixing strategy achieves dispersion equilibration in <40 min, versus hours to days using conventional processing. The resulting scaffolds exhibit high dimensional fidelity, homogeneous ceramic distribution by µCT, excellent batch reproducibility, and significantly enhanced osteogenic differentiation, establishing quantitative processing–structure–property relationships for reproducible high-ceramic DLP bioscaffolds. |
| Proceedings Inclusion? |
Planned: None Selected |
| Keywords |
Additive Manufacturing, Biomaterials, Characterization |