About this Abstract |
| Meeting |
2026 TMS Annual Meeting & Exhibition
|
| Symposium
|
Biological Materials Science
|
| Presentation Title |
Fiber-Oriented Composite Design for Biomimetic Aortic Valve |
| Author(s) |
Yana Portnov, Dekel Maroz, Haim Mordechai, Mirit Sharabi |
| On-Site Speaker (Planned) |
Yana Portnov |
| Abstract Scope |
This study presents the development of a biomimetic aortic valve (AV) construct using silk-
based composite laminates embedded in an interpenetrating polymer network
(IPN) hydrogel matrix to replicate the native AV architecture and mechanical
behavior. One biomimetic design emulated the native fiber architecture, while
a reinforced variant incorporated radial elements to enhance structural
integrity.
Mechanical properties were characterized using uniaxial tensile tests in both
designs and compared to reported properties of native tissue. Valve opening
area and closure dynamics were tested under flow conditions.
The radial reinforced leaflet exhibited improved opening uniformity and
exhibited native-like mechanical behavior. These findings highlight the
importance of directional reinforcement for mimicking native tissue and
supporting the potential of bioengineered valves in future clinical applications. |
| Proceedings Inclusion? |
Planned: |
| Keywords |
Biomaterials, Composites, Other |