| Abstract Scope |
Amyloid fibrils are gaining significant attention as versatile biomaterials owing to their remarkable structural stability, biocompatibility, and tunable properties, with exciting applications in areas such as drug delivery, tissue engineering, biosensing, and development of sustainable packaging. In this work, we present a novel, green synthesis approach for producing amyloid fibrils directly from wheat flour proteins. By optimizing environmentally friendly processing conditions, we demonstrate that wheat flour, a widely available and inexpensive agricultural product, can serve as an effective and sustainable precursor for amyloid fibril formation. This method leverages the natural propensity of wheat proteins to self-assemble into highly ordered nanofibrillar structures, offering a scalable and cheap alternative to traditional amyloid sources, animal or purified proteins. The resulting wheat-derived amyloid fibrils would exhibit promising characteristics for future applications in biosensing, food safety, and environmental monitoring. This study highlights the potential of plant-based, low-cost feedstocks in advancing the development of sustainable biomaterials. |