About this Abstract |
| Meeting |
2026 TMS Annual Meeting & Exhibition
|
| Symposium
|
2026 Technical Division Student Poster Contest
|
| Presentation Title |
SPU-12: Materials-Driven Multimodal Epidermal VOC and TEWL Sensing in Psoriasis and Ichthyosis |
| Author(s) |
Rishi Garg, Sammer Marzouk, Jan-Kai Chang, Taehoon Kim, Jacob Trueb, John A Rogers |
| On-Site Speaker (Planned) |
Rishi Garg |
| Abstract Scope |
Previous research has included an epidermal molecular flux sensor capable of quantifying trans-epidermal water loss (TEWL) through time-dependent concentration measurements in a non-contact chamber with controlled valve response. However, this technology was relatively limited to a single variable.
We enhance this platform for dermatological studies in psoriasis and ichthyosis by extending sensor modality to include volatile organic compounds (VOCs) alongside TEWL, while iterating functional materials and device architecture. VOC (e.g., formaldehyde, ethanol) detection enables quantification of environmental or metabolic triggers for skin barrier dysfunction. Structurally, the resin-printed enclosure incorporates USB-C charging to deliver robustness and replace the electrode-interfacing case. This work provides a testbed to study how processing, structure, and packaging influence sensor performance—linking material selection and chamber barrier function to measurement accuracy and reliability.
We present validation data from bench-top characterization and participant studies to correlate TEWL–VOC response, establishing design principles for next-generation wearable biochemical sensors. |
| Proceedings Inclusion? |
Undecided |
| Keywords |
Electronic Materials, Polymers, Biomaterials |