About this Abstract |
| Meeting |
2027 TMS Annual Meeting & Exhibition
|
| Symposium
|
Magnesium Technology 2027
|
| Presentation Title |
Microstructure Dictates Aluminum Release and Retention in Biomedical Mg-Al Alloys |
| Author(s) |
Sreenivas Raguraman, Mitchell L. Connon, Camryn Byrum, Rohit Berlia, Veronica Ivanovskaya, Beril Ulugun, Suhas Prameela, Roger J. Guillory, Timothy P. Weihs |
| On-Site Speaker (Planned) |
Sreenivas Raguraman |
| Abstract Scope |
Biodegradable Mg alloys are designed to balance mechanical support with controlled corrosion, yet degradation governs the form and biological accessibility of released alloying elements. This is crucial in Mg-Al alloys, where β-Mg17Al12 precipitates alter corrosion behavior and aluminum mobilization. Here, we examine how a processing-controlled microstructure regulates early-stage degradation and Al release in Mg-9Al alloys, using solution-treated and peak-aged conditions to isolate the effects of precipitates. In-vitro immersion tests showed that peak-aged specimens exhibited more localized corrosion and higher total Al release, consistent with micro-galvanic interactions between β-phase and Mg-matrix. However, early-stage 3-day subcutaneous implantation in mice showed the opposite trend, with lower circulating Al in blood for peak-aged implants. This opposing observation suggests that β-containing microstructures promote local retention of Al-rich particulates, whereas solution-treated alloys generate more mobile Al species. These findings show that the microstructure regulates not only the corrosion rate but also the fate of degradation products. |
| Proceedings Inclusion? |
Planned: |
| Keywords |
Magnesium, Biomaterials, Aluminum |