About this Abstract |
| Meeting |
2027 TMS Annual Meeting & Exhibition
|
| Symposium
|
Advanced Biomaterials and Implants
|
| Presentation Title |
Kaolinite-derived mullite-zirconia-magnesia nanobioceramics for antimicrobial implant applications |
| Author(s) |
Dikra Bouras, Manel Sellam, Fouzia Hamadi, Regis Barille |
| On-Site Speaker (Planned) |
Dikra Bouras |
| Abstract Scope |
A hydrothermal autoclave technique was employed for the synthesis of kaolinite-derived mullite–zirconia–magnesia nanobioceramics for antibacterial implant applications. The phase formation, microstructure, and optical properties were analyzed by X-ray diffraction (XRD), scanning electron microscopy coupled with energy dispersive spectroscopy (SEM–EDS), transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FTIR), and ultraviolet–visible (UV–vis) spectroscopy. The obtained results revealed the formation of nanostructured ceramic phases with particles size of 75–103 nm and spherical morphology due to the addition of MgO. The optical band gap of the composite was reduced from 1.91 to 1.43 eV, suggesting an augmentation in the surface reactivity of the composite. The antibacterial assay of the developed bioactive nanoceramics was investigated against Staphylococcus aureus, Bacillus subtilis, and Pseudomonas putida. The MgO-rich composites showed remarkable antibacterial performance with inhibition halo of 38 ± 0.93 mm against S. aureus. The antibacterial mechanism of MgO–ZrO2 composites was explored by reactive oxygen species (ROS) and the nano-bioactive properties of the ceramic. The present study demonstrated the antibacterial potential of kaolinite-derived MgO–ZrO2 composites as anti-infective coatings for implantable medical devices. |
| Proceedings Inclusion? |
Planned: |
| Keywords |
Ceramics, Biomaterials, Magnesium |