| Abstract Scope |
Monitoring neurophysiological activity is essential for evaluating brain function, diagnosing neurological conditions, and guiding therapeutic development. Capturing brain signals in real time offers valuable insights into neural activity and its associated disorders. Traditional electrode materials such as metal, glass, and silicon present challenges, including high impedance, mechanical mismatch with brain tissue, and poor biocompatibility. To address these challenges, we developed a carbon nanotube (CNT) fiber-based array to have stable neural interfaces by reducing electrode diamensions and developing more recording electrode sites using multiple microelectrodes. This neural electrode array consists of 12 hydrogenated nitrile butadiene rubber (HNBR) coated CNT fibers with fire-sharpened ends. For this study, we used ~30 µm diameter CNT fibers as microelectrodes and presented method of assembling polymer-insulated CNT fiber electrodes into an array and acting as one bundle during the brain insertion. Individual electrodes demonstrated lower impedance at 1 kHz and in vitro stable electrochemical performances |