| Abstract Scope |
Additive manufacturing (AM) of titanium (Ti) and its alloys is revolutionizing biomedical implants by enabling patient-specific geometries with optimized mechanical performance. A multiscale surface modification strategy involving nano-topographical engineering and bioactive ceramic coatings can promote early-stage bone attachment and accelerate healing. Porous Ti implants were fabricated using directed energy deposition (DED)-based metal AM technique, followed by electrochemical anodization to form uniform TiO₂ nanotube layers, and calcium phosphate (CaP) coatings, which increase surface roughness and wettability, thereby enhancing protein adsorption and osteoblast attachment. Natural medicinal compounds (NMCs), such as the active compounds of Turmeric (Curcumin), Ginger (Gingerol), Garlic (Allicin), Oregano (Carvacrol/thymol), on these CaP coated Ti and 3D-Printed CaP scaffolds enhance osseointegration. This integrated strategy enables the design of next-generation orthopedic and dental implants with improved biological performance, structural integrity, and long-term reliability. The presentation will discuss the design of next-generation implants tailored to meet clinical needs in treating bone disorders. |