| Abstract Scope |
2D materials offer enormous opportunities to build designer structures with widely tunable properties. The precise atomic engineering and quick characterization approach are critical to advance the application of designer 2D materials. This work introduces new optical features of designer 2D materials, including phonon interference in 2D metals and tellurene, and single photon emission in atomically-engineered transition metal dichalcogenide and boron nitride. We also explored the interaction of 2D materials with organic molecules and related sensing applications. In particular, a novel enhancement effect of molecular Raman signals on 2D surface was discovered, which offers a new paradigm of biochemical sensing with high specificity, high multiplexity, and low noise. Two sensing applications for Alzheimer’s disease and respiratory viruses will also be discussed, which has led to rapid prescreening of disease biomarkers, molecular atlas of the brain to facilitate the understanding of disease pathology, and cell heterogeneity during cancer progression. |