About this Abstract |
Meeting |
MS&T25: Materials Science & Technology
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Symposium
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3D Printing of Biomaterials and Devices
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Presentation Title |
3D printing of active medical devices for transdermal drug delivery and biosensing
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Author(s) |
Roger Jagdish Narayan, Gregory Sachan |
On-Site Speaker (Planned) |
Roger Jagdish Narayan |
Abstract Scope |
Several photopolymerization-based additive manufacturing techniques, such as two photon polymerization and digital micromirror device-based stereolithography, were utilized for the development of small-scale medical devices for transdermal medication delivery and transdermal sensing. Because the two photon process shows nonlinear absorption, two photon polymerization can be used to process medically relevant materials with features that are below the diffraction limit. We manufactured hollow microneedles with two photon polymerization and stereolithography based on digital micromirror devices; these devices might be employed for direct contact between a sensor and tissues below the skin surface. A variety of optical and electrochemical sensors have been combined with arrays of hollow microneedles. Detection of chemicals with multiplexed microneedle sensors has also been demonstrated. Attempts to increase throughput for 3D printing of medical devices and assist with clinical translation will be discussed. |