Biological Materials Science: On-Demand Poster Session
Sponsored by: TMS Functional Materials Division, TMS: Biomaterials Committee
Program Organizers: David Restrepo, University of Texas at San Antonio; Steven Naleway, University of Utah; Jing Du, Pennsylvania State University; Ning Zhang, Baylor University; Hannes Schniepp, William & Mary
Monday 8:00 AM
March 14, 2022
Room: Biomaterials
Location: On-Demand Poster Hall
Cancelled
Design of a Novel Bio-HEA for Potential Use as Orthopedical Implants: Jhuliene Torrento1; Tiago de Sousa1; Carlos Grandini1; Diego Correa2; 1Univ. Estadual Paulista - Laboratório de Anelasticidade e Biomateriais; 2Instituto Federal de Educação, Ciência e Tecnologia de São Paulo
High entropy alloys (HEAs) have been attracted attention by the biomedical industry for their superior strength, ductility, and corrosion resistance. This project aims to design, process, and characterize a novel Bio-HEA for possible application as biomedical implants. In this study, TiNbZrTaMn and TiNbZrTaMo alloys were cast by arc-melting and subjected to thermal treatments. The chemical characterizations indicated good quality of the samples, and the structural characterization indicated majority of BCC crystalline structure, as predicted by the ab initio design. The microstructural characterization showed the formation of irregular structures for the TiNbZrTaMo alloy. In the TiNbZrTaMn alloy, the microstructure was composed of grain boundaries, characteristic of the BCC crystalline structure. The studied samples showed a low elastic modulus (around 80 GPa) and good biocompatibility in relation to some commercial biomaterials. The TiNbZrTaMn sample presented the best combination of properties, showing potential for use as biomaterial. (Financial support: FAPESP, CNPq and CAPES).
Fabrication and Characterisation of Two-layered Synthetic Titanium-Chitosan Bone Scaffolds: Lemiha Yildizbakan1; Vasiliki Panagiotopoulou2; Neelam Iqbal1; Ngoc Do1; Elena Jones1; Peter Giannoudis1; Animesh Jha1; Dina Abdul Aziz1; 1University of Leeds; 2University of Patras
Infection after bone fracture is a common complication that compromises the healing of the damaged bone and may even cause non-union. Infection can also affect the surrounding blood supply, influencing cell growth. The aim of this study was to fabricate and characterize osteogenic and antibacterial bone-mimicking composite scaffolds. The exterior, cortical-like, and porous part was fabricated using titanium powder with 10% iron-doped brushite mineral. The interior,trabecular-like part was fabricated from chitosan, iron-doped brushite, and cerium oxide. The cortical and trabecular components were integrated as one physical structure via freeze-drying. The scaffolds were characterized for their physico-chemical, structural, osteogenic, and antibacterial properties.The minerals and multilayered scaffolds were characterized using light-based techniques (Raman, FTIR, UV-VIS spectroscopy), SEM, Zeta Potential, and X-ray diffraction. The osteogenic properties of the scaffolds were investigated using cytotoxicity and proliferation. The antibacterial properties of the scaffolds were studied against the most common bacteria in bone infection.
Cancelled
Development and Characterization of Novel Ti-Mo-Nb Alloys for Biomedical Applications: Giovana Cardoso1; Carlos Roberto Grandini1; 1UNESP – Univ. Estadual Paulista, Laboratório de Anelasticidade e Biomateriais
Ti and its alloys are widely used for dental and orthopedics implants due to their excellent properties, such as low elastic modulus, high corrosion resistance, and biocompatibility. Recent studies seek to use non-cytotoxic alloying elements, such as Nb and Mo, to develop new Ti beta alloys, as they have better mechanical compatibility than other Ti alloys. Thus, in this study, Ti-5Mo-xNb (x = 0, 10, 20, 30 wt %) alloys were prepared by arc-furnace and their microstructure, and some mechanical properties were measured after an annealing heat treatment. The microstructure, elastic modulus, and microhardness of the alloys were sensitive to the addition of Nb, increasing the amount of beta phase. The alloy with 30% wt of Nb showed the lowest modulus of elasticity value among all studied alloys (73 GPa).