Recent Developments in Biological, Structural and Functional Thin Films and Coatings: Biomedical and Polymeric
Applications
Sponsored by: TMS Functional Materials Division, TMS: Thin Films and Interfaces Committee
Program Organizers: Adele Carrado, University of Strasbourg; Heinz Palkowski, Clausthal University of Technology; Gerald Ferblantier, University of Strasbourg - IUT LP / ICube Laboratory - CNRS; Ramana Chintalapalle, University of Texas at El Paso; Nuggehalli Ravindra, New Jersey Institute of Technology; Nancy Michael, University of Texas at Arlington; Vikas Tomar, Purdue University
Monday 2:30 PM
February 24, 2020
Room: Oceanside
Location: Marriott Marquis Hotel
Session Chair: Adele Carradò, CNRS IPCMS UNISTRA; Nancy Michael, University of Texas Arlington
2:30 PM Keynote
Functionalization of Polymers and Surfaces: a Way to Get Specific and Controlled Host Response towards Implantable Medical Devices: Veronique Migonney1; 1University of Paris
Longer life expectancy leads an increasing of joint pathologies as well as increased demands for medical devices allowing patients to maintain normal physical activity. To solve these societal and economic problems, the combined contributions of chemists, physicists, biomechanists, materials engineers, biologists and surgeons aims to offer increasingly efficient medical implants. Amongst the latest innovations one consists in developing “bioactive polymers and surfaces”, which can be implanted in human bodies without developing foreign host response. Bioactive polymers are macromolecular chains able to mimic biomolecules present in the living system. When grafted or coated on polymer, metallic or ceramic existing prostheses they may lure the living system and the prothesis will be recognized as a “natural” entity associated with no unwanted response. Different methods of grafting bioactive polymers on polymeric and metallic surfaces and the biological in vitro and in vivo responses will be described.
3:10 PM Invited
Surface Color on Demand: Chameleon effect: Karine Mougin1; Hendrik Hoelscher2; 1IS2M-CNRS; 2KIT
Colors affect our everyday life as they provide critical functions in both recognition and communication. Nearly all artifacts of our everyday are manufactured from polymers composed of permanent color; this is a serious problem for manufacturers, as goods cannot be sold anymore when their color is outdated. So, it is of high interest to add color-changing surfaces to manufacturing system. In nature, changing colors are frequently observed in the animal’s world for camouflage by misleading natural enemies or for courting by standing out from the environment. The most prominent examples are chameleons that are able to exhibit complex and rapid color changes during social interactions. The idea was to create a novel hybrid material able to color change of surfaces at will. The key element of this novel technology is based on the combination of two phenomena observed in the nature and transferable to material science: plasmonic and structural colors.
3:40 PM Break
4:00 PM Keynote
Sono-electrodeposition Approach for Biomimetic Calcium-deficient Hydroxyapatite Coating on Carbon Fiber Cloth: Sylvie Bonnamy1; Florian Olivier1; Sandrine Delpeux1; Jérôme Chancolon1; Vincent Sarou-Kanian2; Franck Fayon2; Nathalie Rochet3; 1CNRS/University of Orleans; 2CNRS; 3CNRS/INSERM
Due to their multi-scale organization, breathability and biocompatibility, carbon fiber cloths are considered as tissue engineering. Owing to high bioactivity, osteoconductivity and biocompatibility, calcium phosphate (CaP) are clinically employed in orthopaedics. In this context, CaP and Sr-CaP coatings deposited on carbon cloths are produced by sono-electrodeposition process to be used as bone regenration. FTIR, XRD, HRTEM and SEM show that CaP coatings consist of plate-like and/or needle-like carbonated calcium-deficient hydroxyapatite depending on electrochemical parameters. 1H and 31P MAS NMR show that CaP particles are composed of an ordered and carbonated CDA core associated with a disordered and hydrated surface layer. Biological tests through in vitro osteoblast culture highlight the cell viability. For in vivo biological tests, bone defect is performed on femur of rats. The application of a hybrid material shows an acceleration of bone regeneration. The introduction of drugs to biomaterial components brings new functionalities to the composite biomaterial.
4:40 PM Invited
Determining the Effects of Surface Treatments on the Surface Energy of Titanium in an Effort to Bond a Bioactive Coating: Holly Martin1; Patrick McWhorter1; Ibrahim Al Qanber1; Arthur Kasson1; Snjezana Balaz1; 1Youngstown State University
The surface energy of materials, and their wettability, demonstrate the tendency of a liquid material to spread across solid surfaces. The higher the wettability and surface energy of surface, the more easily a liquid spreads across that surface. The spreading of liquids plays a massive role in the ability of a coating to spread across the surface; the ability of that coating to spread can be affected by changes to the surface energy based on surface modifications. Bonding chitosan to titanium is a multi-step process and examining how these steps affect the surface energy of titanium will determine how to affect the outcome of the coating process. The research presented here will compare the surface energies of surface oxides and individual reaction steps, along with the final chitosan coating to determine the most preferable reaction series for bonding chitosan to titanium.
5:10 PM
Poly(methyl methacrylate) Brushes on Titanium Sheets: Characterization of the Polymer Chains: Martial Morin1; Abdoulaye Ouattara1; Wenjia He1; Patrick Masson1; Geneviève Pourroy1; Heinz Palkowski2; Adele Carrado1; 1IPCMS - CNRS; 2Clausthal University of Technology
The chemical and physical properties of hybrid materials as sandwich titanium (Ti)/Poly(methyl methacrylate) (PMMA)/Ti was tailored by coating with densely grafted PMMA-chains with one end attached to Ti substrate.[1] These surface-tethered PMMA chains stretch out to form brush-like structures in a three-steps process.[2] However, the characterization (molecular weight, polydispersity and glass transition temperature) of PMMA-brushes tethered to surfaces remains challenging. One way to determine these parameters is to cleave polymer brushes from the substrate and measure them directly in solution via size exclusion chromatography, NMR and FTIR. The three-step process was applied with a new specific photocleavable initiator which was grafted covalently onto Ti-surface. The PMMA-chains were growing from functionalized Ti-surface by controlled radical polymerization, then cleaved under UV irradiation from the Ti and finally collected. PMMA-chains were carefully structural and chemical characterized. [1] M.Reggente et al Comp.Structures 218 107-119 2019[2] M.Reggente et al. ACS Appl.Mater.Interfaces 1 5967-5977 2018