Porous Materials for Biomedical Applications: Session I
Sponsored by: ACerS Bioceramics Division
Program Organizers: Usman Liaqat, National University of Sciences and Technology; Chuanbin Mao, University of Oklahoma; Mingying Yang, Zhejiang University

Tuesday 2:00 PM
October 19, 2021
Room: A222
Location: Greater Columbus Convention Center

2:00 PM
Multifunctional Artificial Artery from Direct 3D Printing with Built-in Ferroelectricity and Tissue-matching Modulus for Real-time Sensing and Occlusion Monitoring: Jun Li¹; ¹University of Wisconsin-Madison
    Treating vascular grafts failure requires complex surgery procedures and associates with a high mortality rate. Real-time monitoring vascular systems could initiate safer treatments in the early stage. In this work, an artificial artery was made by processing ferroelectric bio-composite that could be quickly in-situ poled during printing and reshaped into devised objects with superb piezoelectric performance (d33 > 12 pC N-1, confirmed by piezometer) close to commercial ferroelectric polymers. Its designated sinusoidal architecture brought the mechanical modulus down to the same level of human blood vessels. The desired piezoelectric and mechanical properties of the 3D-printed artificial artery provided an excellent sensitivity to pressure change (0.306 mV/mmHg, R2> 0.99) within the range of human blood pressure. The ability to detect subtle vessel motion change enabled early detection of thrombosis, allowing for preventing grafts failure. This work demonstrated a promising strategy of incorporating multi-functionality into artificial biological systems for smart healthcare systems.

2:20 PM
Synthesis and Characterization of Porous Diopside Scaffold Synthesized Using Rice Husk as a Space Holder Material for Orthopedic Application: Mayank Yadav¹; Vaibhav Pandey¹; Jyoti Kumari¹; Kalyani Mohanta¹; Vinay Singh¹; ¹Indian Institute of Technology (BHU), Varanasi
    Diopside (Di) is a bioceramic with excellent bioactivity and mechanical property, due to its appropriate degradation rate and biocompatibility it can act as a bone substitute for bone tissue engineering. The study was focused on the development of a porous Di scaffold fabricated via the space holder (SH) technique. Rice Husk (RH) powder of different particle sizes was used as SH. Porous Di scaffold was characterized by means of X-ray Diffraction, SEM, the Archimedes method, and Compression tests. The result shows that Di scaffold has 45-50% apparent porosity and interconnected pore geometry with compressive strength in the range of (1.4-1.6 MPa). In vitro study was conducted by immersing the porous scaffold in the SBF solution for 21 days and apatite forming ability was examined through SEM and EDS analysis. The results suggest that scaffold can be used as a bone substitute for bone tissue engineering.