Surface Treatments and Properties of Titanium and Titanium Alloys: A Forum on New Strategies and Processes for Biomedical and Industrial Advanced Applications: Surface Treatments and Properties of Titanium and Titanium Alloys
Program Organizers: Silvia Spriano, Politecnico di Torino; Sara Ferraris, Politecnico di Torino; Paulo Tambasco de Oliveira, Universidade de São Paulo,; Antonio Nanci, Université de Montréal

Wednesday 8:00 AM
November 4, 2020
Room: Virtual Meeting Room 10
Location: MS&T Virtual

Session Chair: Silvia Spriano, POLITECNICO DI TORINO; Sara Ferraris, POLITECNICO DI TORINO


8:00 AM  
Introductory Comments: Surface Treatments and Properties of Titanium and Titanium Alloys:: Silvia Spriano1; 1Politecnico De Torino
    Introductory Comments

8:05 AM  
Controlled Surface Topography of Titanium-based Implants via Use of Gas/Solid Reactions: Naotaka Ogura1; Pavan Srivas1; Kenneth Sandhage1; 1Purdue University
    The surface topography of a titanium-based biomedical implant can have a significant influence on osseointegration. Conventional methods for controlling the surface roughness, from the microscale down to the nanoscale, of such implants have involved line-of-sight methods that are limited to external surfaces. Given the advent of 3-D printing of macroporous titanium-based implants, new methods are needed for tailoring the topography of internal surfaces of such implants. We will present a novel, non-line-of-sight method for achieving controlled surface roughness of internal and external surfaces down to the nanoscale via the use of sequential gas/solid reactions. Titanium or titanium alloy surfaces are first exposed to a thermal oxidation treatment to generate a thin continuous oxide scale of tailorable thickness. This oxide scale is then allowed to react further to generate a composite scale. Partial selective dissolution then yields thin, uniformly nanoporous/nanorough surfaces.

8:25 AM  
Sustainable Antibacterial Activity of Iodine-loaded Bioactive Titanium Metal by Chemical and Heat Treatment: Seiji Yamaguchi1; Morihiro Ito1; Seine Shintani1; Takashi Nakamura1; Hiroaki Takadama1; 1Chubu University
    The demand for prevention of infection as well as faster bone bonding is sharply increasing in orthopaedic and dental implants. In this study, conventional NaOH solution and heat treatment that allows Ti and its alloys bond to living bone was modified to induce calcium and iodine ions into the metal surfaces. As a result, iodine-containing calcium titanate with the 7.3 – 10.3 % of iodine was produced on the metals. The treated metals formed bone-like apatite in a simulated body fluid within 3 days, and exhibited high antibacterial activity against to methicillin-resistant Staphylococcus aureus, Staphylococcus aureus, and Escherichia coli (more than 99% reduction) without any cytotoxicity. This high reduction rate of bacteria almost maintained even if the treated Ti had been preserved under simulated body environment for a long period of half year (97.3% reduction). The treated metals with iodine-containing calcium titanate should be useful for orthopaedic and dental implants.

8:45 AM  
A Comparative Study of Protein Adsorption on Different Bio-surfaces for Osteointegration: Jacopo Barberi1; Sara Ferraris1; Luisa Mandrile2; Lucia Napione1; Erik Piatti1; Andrea Mario Rossi2; Seiji Yamaguchi3; Silvia Spriano1; 1Politecnico di Torino; 2National Institute of Metrological Research; 3Chubu University
    Understanding protein adsorption is of great interest in the development and engineering of novel medical devices, due to proteins effect in mediating cell-implant interactions. This work aims to investigate the adsorption of bovine serum albumin on different types of bio-surfaces intended for osteointegration. Furthermore, to develop a set of characterization techniques that can be applied on a wide variety of different materials. In particular, four different treatments on Ti or Ti6Al4 alloy and an Ag-doped bioactive glass were chosen, along with polystyrene. The surface properties of the substrates prior and after BSA adsorption were investigated through common techniques (FESEM, EDS, XPS and BCA) combined with less conventional ones (surface zeta potential, KPFM and spectroscopic techniques, SERS and ATR-FTIR). The results provide insight on the effects of the different surface compositions, functional groups and topography on the adsorption of albumin. Total amount and conformation of the adsorbed protein are both investigated.