Late News Poster Session: Biomaterials
Program Organizers: TMS Administration
Tuesday 5:30 PM
March 1, 2022
Room: Exhibit Hall C
Location: Anaheim Convention Center
K-16: DFT Screening of Exciton Delocalization and Coupling Properties of Dyes for Aggregate Systems: Maia Ketteridge1; German Barcenas1; Austin Biaggne1; Lan Li1; 1Boise State University
Dye aggregates systems have been shown to exhibit exciton delocalization, which has applications in the study of quantum information. Maximizing exciton exchange energy (J) and exciton-exciton interaction energy (K) are of particular interest for dye-aggregate systems, and computational screening of potential dyes can identify those dyes with desired properties for further experimental and computational investigation. This process reduces time and resources spent experimentally measuring dye properties. We detail a method for high-throughput screening of dyes using density functional theorem (DFT) and time-dependent density functional theorem (TD-DFT). Transition dipole moment and static dipole difference are calculated, which J and K depend upon. The effects of solvent can also be estimated. The method was applied to modified Cy5 dye in water and vacuum. Several interesting substituents were identified for further experiment.
K-17: Electrochemical Thyroxine Detection Using Copper Metal Organic Framework and Polyaniline Composite: Mradula Mradula1; 1CSIR-Central Scientific Instruments Organization
The Cu-MOF@PANI@Ab modified SPCE used as a sensing platform. Cu-MOF and their composite were characterized by field emission scanning electron microscopy (FESEM), Fourier transform infrared spectroscopy (FTIR), RAMAN spectroscopy, X-ray diffraction (XRD), cyclic voltammetry (CV), and differential pulse voltammetry (DPV). The immunosensor possessed a dynamic linear range (10–105 pM) with a low limit of detection (LOD) of 0.33 pM (0.25 pg/ml) for CV and 0.17 pM (0.13 pg/ml) for DPV. The evaluation study of immunosensor displayed a good analytical recovery of ≥ 90%, when different concentration of thyroxine was added in the serum sample. In addition, to determine the reproducibility for working electrode between and within batch, the relative standard deviation calculated were 3.87% and 6.04%, respectively, represent it's good reproducibility. The immunosensor retained 90% of its initial activity after its regular use for 40 days, while being stored at 4 °C.
K-18: Stretchable-ion Responsive Hydrogel and Its Rheology: Abhishek Pachauri1; Jeffrey Bates1; 1University of Utah
Hydrogels are superb candidates for biomedical applications because of their magnificent biocompatibility. Here, a stretchable hydrogel with ion-responsive properties is synthesized. The hydrogel can swell considerably when placed in a phosphate buffer solution and the kinetics of swelling is studied. Mechanical tests are carried out on the hydrogel to evaluate its strength, elastic modulus, and toughness. For analyzing the 3 D printability of the hydrogel, rheological characterization is done.