Recent Developments in Biological, Structural and Functional Thin Films and Coatings: Biomaterials and Functional Films
Sponsored by: TMS Functional Materials Division, TMS: Thin Films and Interfaces Committee
Program Organizers: Adele Carradò, Université de Strasbourg IPCMS; Nancy Michael, University of Texas at Arlington; Ramana Chintalapalle, UTEP; Heinz Palkowski, Clausthal Univ of Technology; Vikas Tomar, Purdue Univ; Nuggehalli Ravindra, NJIT

Monday 8:30 AM
February 27, 2017
Room: Pacific 18
Location: Marriott Marquis Hotel

Session Chair: Adele Carradò, Université de Strasbourg IPCMS; Heinz Palkowski, TU Clausthal IMET

8:30 AM  Keynote
Osteogenic Potential of a Biomimetic Layer-by-layer Platform: Khalil Abdelkebir1; Fabien Gaudière1; Laura Tesson1; Jean-Pierre Vannier1; Hassan Atmani1; Sandrine Morin-Grognet1; Béatrice Labat1; Guy Ladam1; 1University of Rouen Normandy
    Implant osseointegration remains a continuing challenge in bone surgery. Biomimetic Layer-by-Layer (LbL) coatings comprising chondroitin sulfate A, a biological polyanionic glycosaminoglycan of bone tissue, and poly-L-lysine, a polycationic polypeptide, are promising, versatile candidates for inducing biomineralization directly at implant surfaces. In a first, physico-chemical approach, films enriched with phosphoproteins displayed unique, promoting influence on the heterogeneous nucleation of calcium phosphate, leading to thin uniform layers of biologically-relevant mineral phases. In a second, biological approach, cytophilicity of the LbL coatings was improved by treatments with genipin, a biological crosslinking agent with less cytotoxicity than current chemical crosslinkers. Structural changes within the LbL films were elucidated, in particular by means of a newly discovered FRET couple involving genipin. The osteogenic potential of genipin-treated LbL films was clearly enhanced in vitro. A complementary approach based on osteogenic drugs embedded into the LbL films used as nanoreservoirs is ongoing.

9:10 AM  
Synthesis of CNT Reinforced Hydroxyapatite Coatings over Bio Materials Surfaces through Electrodepositions: Rajib Chakraborty1; Srijan Sengupta1; Partha Saha1; Karabi Das1; Siddhartha Das1; 1Indian Institute of Technology, Kharagpur
    The orthopedic implants are made of bio-compatible stainless steels or titanium based alloys. However, none of these materials is as capable for faster tissue or cell growth on the implants as compared to natural bone surface. Keeping in view of the natural bone compositions (hydroxyapatite and its group compound along with collagen fiber reinforcement), this work reports the development of a bio-compatible coating of CNT reinforced hydroxyapatite and its group compound through electrodepositions. The deposited coating (thickness ~ 80 micrometer) consists of both crystalline and amorphous phases (around 30%). The vacant space created by dilution of amorphous phase on interaction with body fluid, initiate tissue growth inside the coating and thus enhances the bonding between implant and tissues. The crystallite size was found to be in between 15 to 70 manometer. Different morphology of coating along with varying micro roughness and lattice strain were observed at various current densities.

9:30 AM  
Osteoanabolic Implant Materials for Orthopaedic Treatment: Xiaobo Chen1; Yun-Fei Ding1; Rachel Li2; M. Nakai3; M. Niinomi3; Paul Smith2; Nick Birbilis1; 1Monash University; 2The Australian National Universtiy; 3Tohoku University
    Osteoporotic bone is more prone to fracture than normal bone, and current orthopaedic implant materials are not ideal for the osteoporotic cases. A newly developed strontium phosphate (SrPO4) coating is reported herein, as applied to Ti-29Nb-13Ta-4.6Zr (wt.%), TNTZ, an implant material with a comparative Young’s modulus to that of natural bone. TNTZ with excellent biocompatibility and high bio-inertness was pretreated in a concentrated alkaline solution under hydrothermal conditions, followed by a hydrothermal coating growth process to achieve complete SrPO4 surface coverage with high bonding strength. Owing to the release of Sr ions from the SrPO4 coating and its unique surface topography, osteoblast cells demonstrated increased proliferation and differentiation, whilst the cellular responses of osteoclasts were suppressed, compared to the control case, i.e. bare TNTZ.

9:50 AM Break

10:10 AM  Keynote
Multifunctional Magnetic Biomaterials: Dendronized Nanoparticles and Magnetic Microbubbles: Geneviève Pourroy1; 1CNRS University of Strasbourg-IPCMS
    Multifunctional nanoparticles are promising biomaterials for imaging. Core-shell magnetic nanoparticles offer the possibility to combine two types of imaging. Magnetic resonance imaging (MRI) can be combined with an optical signal brought by the shell in colloidal suspensions or with ultrasounds in magnetic microbubbles. After an overview on the elaboration of core-shell nanoparticles and their stabilization in aqueous media, we will present the elaboration of dendronized iron oxide for imaging sentinel nodes in cancer therapy and the use of perfluoroalkyl phosphate to stabilize magnetic microbubbles.

10:50 AM  
Comparing Various Corrosion Inhibitors Absorbed on to Chitosan bonded to Steel and the Resulting Corrosion Protection: Holly Martin1; Stephen Cornich1; John Crowe1; Jacob Millerleile1; Snjezana Balaz2; 1Department of Chemical Engineering, Youngstown State University; 2Department of Physics and Astronomy, Youngstown State University
    Corrosion related issues currently cost 3% of the worldwide GDP, so reducing corrosion can greatly diminish these costs. Coatings that can withstand water, salt, and mechanical stresses, such as indentation and scratching, presents one way of reducing corrosion of the steel in oil and gas pipelines. Chitosan, a derivative of shrimp shells, can withstand chlorides from saltwater and is bacterialcidal, potentially killing various corrosion inducing microbes. However, chitosan also allows water to pass through, thus not preventing water-based corrosion. Because chitosan is a large molecule, with linker molecules used to bond it to steel, this also presents an opportunity to suspend other corrosion inhibiting molecules between the chitosan polymer chains. The research presented here will detail the effects of various corrosion inhibitors absorbed into the corrosion of chitosan bonded to steel exposed to two different corrosive environments, a salt-spray environment and an immersion environment.

11:10 AM  
Development of Enamel Coatings in Accordance with Recent Regulations of Food Contact Materials: Meltem Ipekci1; Kagan Benzesik1; Onuralp Yucel1; Filiz Cinar Sahin1; Alper Yesilcubuk2; 1Istanbul Technical University; 2Arçelik A.Ş.
    The holding ability of enamel on substrate can be provided by different mechanisms such as chemical bonding. Chemical bonding can be achieved by the diffusion of FeO from the substrate to the enamel, and the diffusion of oxides such as NiO and CoO from enamel to the substrate. In this study, we used frit containing NiO and CoO in enamel according to the recent regulations of food contact materials in order to investigate the effects of these metal oxides on the holding ability of enamel. Firing temperature was kept stable at 830°C during the experiments, and firing times were 2 and 5 min, so we also observed the effect of firing time at stable temperature. After the trials, migration tests and ICP MS analysis were performed to determine the amount of the Ni and Co which can migrate to food from the enamel. Moreover, impact tests were carried out to determine the holding abilities of enamel in terms of firing time.

11:30 AM  
Super-stretchable Metallic Interconnect Films with a Linear Strain of up to 100%: Yeasir Arafat1; Indranath Dutta1; Rahul Panat1; 1Washington State University
    Flexible metallic interconnects are highly important in wearable devices used in emerging areas such as soft robotics, human health monitoring, and sportsware. Metal interconnects in such devices are heterogeneous metal-polymer systems that sustain large deformation in the form of stretching and/or bending without failure. In this work, we present a material system and the mechanics of highly stretchable metallic interconnects. The material system consisted of Indium metal film over an elastomer (PDMS) with a discontinuous Cr adhesion layer such that the metal interconnect is shown to stretch to extremely high linear strain (up to 100%) without failure during repeated cycling. We also investigate the mechanisms that allow such films to be stretched by mapping the strain field of the Cr adhesion interlayer and the In interconnect film. We show that the Cr interlayer morphology, consisting of islands separated by bi-axial cracks, accommodates the strain by widening of the Cr cracks.