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Meeting 2021 TMS Annual Meeting & Exhibition
Symposium Bio-Nano Interfaces and Engineering Applications
Presentation Title The Mechanical Significance of Sublamellar Organization of Mineralized Collagen Fibrils
Author(s) Sermin F. Utku
On-Site Speaker (Planned) Sermin F. Utku
Abstract Scope Bone consists mainly of Type I Collagen, hydroxyapatite, mucopolysaccharides and bone fluid. The collagen and mineral plate orientations affect bone mechanics. The organic component of lamellar bone was modelled to contract towards the mineral by dehydration, forming a contraction vector as the surface normal of the mineral plate. The amount of dehydration based contraction in the rotated collagen fibrils was calculated for the sublamellar model, where the mineral plate of the 0° [001] sublamellar collagen fibril was oriented along the y (010) plane. Projections of sublamellar contraction vectors were denoted as u, v and w displacements at 10°-20°-30° angles and summed to give the lamellar total and the anisotropy ratios of properties in directions parallel (w) versus perpendicular (u or v) to the osteon. The large variation in calculated wet and dry bone anisotropy ratios demonstrates the significance of the effect of collagen and mineral plate orientation on bone mechanics.
Proceedings Inclusion? Planned:
Keywords Biomaterials, Composites, Mechanical Properties

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Detection of Limonene Using Graphene Field Effect Transistor Modified by Self-assembling Peptide
Developing Nanostructured Metals for Innovative Medical Implants with Improved Design and Biofunctionality
Enhancing Electrochemical Detection of Choline Using Molecularly Imprinted Polymer Electrode
Flexible-glass Like Coating onto PTFE Vascular Graft Material via Nonthermal Plasma Process
Insight into the Mechanobiological Progression of Cancer Metastasis to Bone
Stickiness at Bio-nano-interfaces: From Nanoscale Characterization to Macroscale Properties
The Mechanical Significance of Sublamellar Organization of Mineralized Collagen Fibrils

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