|About this Abstract
||2018 TMS Annual Meeting & Exhibition
||Biological Materials Science
||Synthesis of PVA Scaffolds with Gradient Porous Structures by Freeze Casting
||Ching-Chun Chiu, Haw-Kai Chang, Hsin-Juei Wang, Po-Yu Chen
|On-Site Speaker (Planned)
Freeze casting is a novel technique to synthesize bio-inspired scaffold with unidirectional porous structure. Extensive studies have focused on ceramic-based scaffolds and composites. In this study, polymer-based, polyvinyl alcohol (PVA) scaffolds were synthesized by freeze casting of aqueous solution. The pore size, channel width and porosity of PVA scaffolds can be varied by altering concentration of solution, cooling rate, and other experimental parameters. PVA scaffolds with radially and longitudinally gradient porous structures were synthesized. The microstructure was characterized by SEM and average pore size was measured by mercury intrusion. The mechanical properties of scaffolds were evaluated by compression tests. Results showed that PVA scaffolds exhibited viscoelastic behavior and can recover to original shape after cyclic compressive loadings and the compressive strength of scaffolds can be enhanced by increasing the degree of cross-linking. The biocompatible and biodegradable PVA scaffolds with gradient porous structures can be potentially applied in the biomedical fields.
||Planned: Supplemental Proceedings volume