| About this Abstract |
| Meeting |
2011 TMS Annual Meeting & Exhibition
|
| Symposium
|
Surfaces and Heterostructures at Nano- or Micro-Scale and Their Characterization, Properties, and Applications
|
| Presentation Title |
Synthesis of Magnetic and Fluorescent Bifunctional Nanoparticles |
| Author(s) |
Yaolin Xu, Soubantika Palchoudhury, Yuping Bao |
| On-Site Speaker (Planned) |
Yuping Bao |
| Abstract Scope |
Magnetic nanoparticles (MNP) have significantly advanced cancer treatments through targeted drug delivery and localized therapy. MNPs further make simultaneous therapy and diagnosis possible as magnetic resonant imaging (MRI) contrast agents. Unfortunately, the studies of simultaneous therapy and diagnosis of MNPs are limited by the expensive MRI equipment. Currently, fluorescence imaging remains the primary choice for bio-imaging because of its high sensitivity. Here, we reported magnetic-fluorescent integrated nanoparticles using iron oxide as the magnetic component and metallic nanoclusters as the fluorescent component. Iron oxide nanoparticles were synthesized using a modified co-precipitation method by introducing a capping molecule during synthesis. Subsequently, these iron oxide nanoparticles were used as seeds for the synthesis of Ag metallic nanoclusters. Around 10 nm iron oxide nanoparticles were successfully produced, followed by attachment of fluorescent clusters with a broad emission in the range of 600 -650 nm. This work is funded by NSF-DMR 0907204 |
| Proceedings Inclusion? |
Planned: A CD-only volume |