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Meeting 2021 TMS Annual Meeting & Exhibition
Symposium Frontiers of Materials Award Symposium: Radiation Processing of Materials
Presentation Title Direct Prompt Synthesis of Radioactive Nanoparticles (Prompt Nano Radioisotopes)
Author(s) Carlos H. Castano
On-Site Speaker (Planned) Carlos H. Castano
Abstract Scope Most nanomedicines use nanostructures as carrier for drugs, making their therapeutic effectiveness dependent on the ability to deliver the drug to the interior of cells (endocytosis). Nano Radioisotopes do NOT require endocytosis, since approaching the cell from the outside (targeting or retention) can be sufficient to kill the cell (i.e. induce apoptosis). In this case, the therapeutic load is radiating energy with sufficient penetration into nearby cells. Radiation methods for the creation of nanostructures also have various advantages over chemical ones. First, the reductive potential induced by radiation is essential instantaneous and uniform throughout the precursor solutions. Finally, the reducing agent is radiation, ameliorating potential contamination issues. Most radioactive nanostructures (non-prompt) are produced by activating precursor elements and then performing radiochemical procedures to make nanostructured forms. Prompt Nano-Radioisotopes make radioactive isotopes in nano form ready to use, reducing the need for facilities to manipulate radiochemicals or radiopharmaceuticals.
Proceedings Inclusion? Planned: None Selected

OTHER PAPERS PLANNED FOR THIS SYMPOSIUM

Direct Prompt Synthesis of Radioactive Nanoparticles (Prompt Nano Radioisotopes)
Introductory Comments: Frontiers of Materials Award Symposium: Radiation Processing of Materials
Ionizing Radiation in the Synthesis and Processing of Nanocomposites for Medical and Environmental Applications
Ionizing Radiation Synthesis of Novel Fabrics for Extraction of Uranium from Seawater
Nanochannels, Nanowires, and Nanotubes Fabricated by Ion-track Nanotechnology
Probing and Processing Nanomaterials and Devices with Radiation
Radiation-grafting of Smart Polymers for Potential Biomedical Applications

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