Graduate science and engineering programs prepare scientists for the practice and application of science. As such, PhD's generally thrive in technical roles. However, in a startup environment, pure technical roles do not truly exist. This talk will describe the speaker's experience in materials entrepreneurship at Desktop Metal, a metal additive manufacturing startup. It will touch on some of the difficulties faced in transitioning from academia to startup culture, practical management and leadership strategies for small teams, building a materials research and development team, and practical resources young scientists can take advantage of to learn about business and entrepreneurship during their graduate studies. Substantial time will be left at the end for questions.