Greg Olson’s vision for Materials by Design started with a simple precept; with the advent of computational tools for thermodynamic, kinetics, and mechanics, can we design materials is the same way that mechanical and electrical components were being designed? Combining systems engineering principles, optimization schemes and stretching the computational capabilities of the 1980s, the first computationally designed material was completed for the space shuttle main turbo-pump bearings. While it wasn’t implemented, the lessons learned refined subsequent efforts, and soon materials designs were underway for car bodies, armor plate, aircraft landing gear, high-power density transmissions, advanced Ni-superalloys and even high-performance bubble gum. Widespread acceptance of Materials by Design was initially slow, but and soon the Accelerated Insertion of Materials and subsequent programs, including the MGI, provided support of the initial ideals of MbD. Today, hundreds of millions of people experience products incorporating computationally designed materials in consumer electronics, transportations and aerospace.