|About this Abstract
||Materials Science & Technology 2011
||Next Generation Biomaterials
||Multi-Scale Porosity in Artificial Bone Scaffolds by Robocasting
||Yang Shi, James Earl Smay
|On-Site Speaker (Planned)
Natural bone has a complex pore structure with variation in pore size, pore shape and connectivity in three dimensional space. Rapid prototyping is a logical tool for design of artificial bone scaffold structures since tri-calcium phosphates can easily be printed as a cylindrical lattice structure having struts and pores commensurate with cancellous bone. In this work, we present data on the assembly of scaffolds that have porosity on multiple length scales: from the macro porosity of the lattice structure to micro and nano-porosity produced by fugitive particle burnout. An in-situ mixing nozzle is used to blend varying amounts of polymer porogens into a tri-calcium phosphate colloidal paste as a function of radial position. Hence the amount of porosity is controlled by the spatial position and the selected composition of the paste dispensed at that location in the construct. The pore network is analyzed by x-ray tomography and scanning electron microscopy.