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Meeting 2016 TMS Annual Meeting & Exhibition
Symposium Magnesium-based Biodegradable Implants
Presentation Title Computer Simulation of the Mechanical Behaviour of Implanted Biodegradable Stents in a Remodelling Artery
Author(s) Peter Edward McHugh, Enda L Boland
On-Site Speaker (Planned) Peter Edward McHugh
Abstract Scope One of the most fertile growth areas in coronary stenting technology is biodegradation; here there is the possibility to generate stents that will break down in the body after the initial necessary scaffolding period (6-12 months) and when the artery has remodelled. Magnesium alloys are very attractive as materials for this application and commercial stents are now in clinical trials. In this work a novel magnesium corrosion finite element model is presented that describes both uniform corrosion and heterogeneous pitting corrosion. The model is implemented in a finite element model of an artery with a deployed magnesium stent, and the scaffolding support of the stent is predicted over time as the stent degrades. The artery model is enhanced to include the representation of neo-intimal remodelling, as a result of the initial angioplasty injury, allowing the assessment of the effects of arterial remodelling on loss of scaffolding support during stent degradation.
Proceedings Inclusion? Planned: A combination print-CD volume


Absorbable Filament Technologies: Wire-drawing to Enable Next-generation Medical Devices
Appropriate Corrosion-FatigueTesting of Magnesium Alloys for Temporary Bio-implant Applications
Computer Simulation of the Mechanical Behaviour of Implanted Biodegradable Stents in a Remodelling Artery
Degradation of MgF2-coated and Uncoated MgNd2 Specimens in Contact with Nasal Mucosa
Fabrication, Testing and Performance of Rare Earth-containing Magnesium Biodegradable Metals
In Vitro Corrosion and Cytocompatibility Properties of Mg-2Gd-X(Ag, Ca) Alloys
Influence of Precipitation Hardening in Mg-Y-Nd on Mechanical and Corrosion Properties
Magnesium-based Compression Screws
Magnesium Powder Injection Molding (MIM) of Orthopedic Implants for Biomedical Applications
Manufacturing of Osteosynthesis Systems Made of Magnesium Alloy AZ91
Monitoring Biodegradation of Magnesium Implants with Sensors
Plasma Surface Modification of Magnesium-Based and Related Biomaterials
Standardized Guidance for the Preclinical Evaluation of Absorbable Metal Implants
The Industrial Challenges of Manufacturing Bioabsorbable Magnesium
Understanding Corrosion-assisted Cracking of Magnesium Alloys for Bioimplant Applications

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