|About this Abstract
||2017 TMS Annual Meeting & Exhibition
||Biological Materials Science
||H-23: Development of 3D Template Freeze Casted Hydroxyapatite/Magnesium Alloy Biodegradable Implants
||Yajur Maker, Jae-Young Jung, Kathryn Kang, Michael Frank, Joanna McKittrick
|On-Site Speaker (Planned)
Resorbable bone implant materials have been actively researched and developed for use in biomedical applications. One such biocompatible material is hydroxyapatite (HA), which provides exceptional osteoconductivity, but significantly lacks mechanical strength under freeze casting preparation. To compensate for the lack of mechanical strength we have proposed a new freeze casted HA scaffold encased inside a magnesium (Mg) alloy shell which safely biodegrades within the body. In this process three novel concepts are being explored: (1) the use of a new biocompatible Mg alloy that is shown to have a degradation rate similar to bone growth, (2) the fabrication of bone-like HA scaffolds with enhanced processing control of the macro/micro porosity using a 3D template, and (3) the preparation of the Mg alloy encasing the HA scaffold, in order to combine the positive characteristics of the two materials (Mg alloy’s strength and HA’s osteoconductivity) in forming a comprehensive biodegradable implant.
||Planned: Supplemental Proceedings volume